Title |
Synthesis of naringin 6"-ricinoleate using immobilized lipase
|
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Published in |
BMC Chemistry, May 2012
|
DOI | 10.1186/1752-153x-6-41 |
Pubmed ID | |
Authors |
Verônica M Almeida, Carla RC Branco, Sandra A Assis, Ivo JC Vieira, Raimundo Braz-Filho, Alexsandro Branco |
Abstract |
Naringin is an important flavanone with several biological activities, including antioxidant action. However, this compound shows low solubility in lipophilic preparations, such as is used in the cosmetic and food industries. One way to solve this problem is to add fatty acids to the flavonoid sugar unit using immobilized lipase. However, there is limited research regarding hydroxylation of unsaturated fatty acids as an answer to the low solubility challenge. In this work, we describe the reaction of naringin with castor oil containing ricinoleic acid, castor oil's major fatty acid component, using immobilized lipase from Candida antarctica. Analysis of the 1H and 13 C NMR (1D and 2D) spectra and literature comparison were used to characterise the obtained acyl derivative. |
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