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Synthesis of naringin 6"-ricinoleate using immobilized lipase

Overview of attention for article published in BMC Chemistry, May 2012
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Title
Synthesis of naringin 6"-ricinoleate using immobilized lipase
Published in
BMC Chemistry, May 2012
DOI 10.1186/1752-153x-6-41
Pubmed ID
Authors

Verônica M Almeida, Carla RC Branco, Sandra A Assis, Ivo JC Vieira, Raimundo Braz-Filho, Alexsandro Branco

Abstract

Naringin is an important flavanone with several biological activities, including antioxidant action. However, this compound shows low solubility in lipophilic preparations, such as is used in the cosmetic and food industries. One way to solve this problem is to add fatty acids to the flavonoid sugar unit using immobilized lipase. However, there is limited research regarding hydroxylation of unsaturated fatty acids as an answer to the low solubility challenge. In this work, we describe the reaction of naringin with castor oil containing ricinoleic acid, castor oil's major fatty acid component, using immobilized lipase from Candida antarctica. Analysis of the 1H and 13 C NMR (1D and 2D) spectra and literature comparison were used to characterise the obtained acyl derivative.

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The data shown below were compiled from readership statistics for 32 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Brazil 2 6%
India 1 3%
Unknown 29 91%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 7 22%
Student > Master 6 19%
Researcher 4 13%
Student > Bachelor 3 9%
Professor 1 3%
Other 3 9%
Unknown 8 25%
Readers by discipline Count As %
Chemistry 11 34%
Engineering 4 13%
Agricultural and Biological Sciences 4 13%
Chemical Engineering 1 3%
Environmental Science 1 3%
Other 2 6%
Unknown 9 28%