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Human cyclin T1 expression ameliorates a T-cell-specific transcriptional limitation for HIV in transgenic rats, but is not sufficient for a spreading infection of prototypic R5 HIV-1 strains ex vivo

Overview of attention for article published in Retrovirology, January 2009
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Title
Human cyclin T1 expression ameliorates a T-cell-specific transcriptional limitation for HIV in transgenic rats, but is not sufficient for a spreading infection of prototypic R5 HIV-1 strains ex vivo
Published in
Retrovirology, January 2009
DOI 10.1186/1742-4690-6-2
Pubmed ID
Authors

Nico Michel, Christine Goffinet, Kerstin Ganter, Ina Allespach, Vineet N KewalRamani, Mohammed Saifuddin, Dan R Littman, Warner C Greene, Mark A Goldsmith, Oliver T Keppler

Abstract

Cells derived from native rodents have limits at distinct steps of HIV replication. Rat primary CD4 T-cells, but not macrophages, display a profound transcriptional deficit that is ameliorated by transient trans-complementation with the human Tat-interacting protein Cyclin T1 (hCycT1).

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 18 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 1 6%
Unknown 17 94%

Demographic breakdown

Readers by professional status Count As %
Researcher 7 39%
Professor 3 17%
Student > Ph. D. Student 3 17%
Professor > Associate Professor 2 11%
Other 1 6%
Other 2 11%
Readers by discipline Count As %
Agricultural and Biological Sciences 8 44%
Immunology and Microbiology 4 22%
Biochemistry, Genetics and Molecular Biology 4 22%
Arts and Humanities 1 6%
Chemical Engineering 1 6%
Other 1 6%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 28 February 2012.
All research outputs
#20,157,329
of 22,665,794 outputs
Outputs from Retrovirology
#1,059
of 1,102 outputs
Outputs of similar age
#163,919
of 169,631 outputs
Outputs of similar age from Retrovirology
#7
of 8 outputs
Altmetric has tracked 22,665,794 research outputs across all sources so far. This one is in the 1st percentile – i.e., 1% of other outputs scored the same or lower than it.
So far Altmetric has tracked 1,102 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 7.0. This one is in the 1st percentile – i.e., 1% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 169,631 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 8 others from the same source and published within six weeks on either side of this one.