The effects of the DNA Demethylating reagent, 5-azacytidine on SMCHD1 genomic localization. https://t.co/2S5HgL8dUv https://t.co/ShlR2dwE48
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Furthermore, SMCHD1 was shown to be involved in de novo methylation of the DUX4-encoding D4Z4 macro-satellite repeat regulated by CTCF/CTCFL-binding sites https://t.co/HWgOc2GwBC
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The effects of the DNA Demethylating reagent, 5-azacytidine on SMCHD1 genomic localization. While 5-azaC causes degradation of DNMT1 and DNA demethylation in human cancer cell lines, it removes repressive CpG-methylation from CTCFL and activates BORIS CTA.
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The effects of the DNA Demethylating reagent, 5-azacytidine on SMCHD1 genomic localization. https://t.co/X0jLlVHemb