The main challenge is scalability, especially with the exponential growth in single-cell datasets and advent of new modalities or multi-omics. This will be informed by their benchmarking study of PCA. (I've found this a limiting step in my analyses.) http
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4,008 followers
RT @LibKot: Benchmarking principal component analysis for large-scale single-cell RNA-sequencing https://t.co/RjktLlth2Q #maskotlib
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自分は単純なランダムサンプリングがクラスタリング精度を損なうことは確認していたが(https://t.co/ZKavQErjrF )、こういう工夫はしたことが無いので機会があれば試したい。
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RT @AedinCulhane: Benchmarking principal component analysis for large-scale single-cell RNA-sequencing & importance of lazy loading; Defer…