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Metaprotein expression modeling for label-free quantitative proteomics

Overview of attention for article published in BMC Bioinformatics, May 2012
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Title
Metaprotein expression modeling for label-free quantitative proteomics
Published in
BMC Bioinformatics, May 2012
DOI 10.1186/1471-2105-13-74
Pubmed ID
Authors

Joseph E Lucas, J Will Thompson, Laura G Dubois, Jeanette McCarthy, Hans Tillmann, Alexander Thompson, Norah Shire, Ron Hendrickson, Francisco Dieguez, Phyllis Goldman, Kathleen Schwarz, Keyur Patel, John McHutchison, M Arthur Moseley

Abstract

Label-free quantitative proteomics holds a great deal of promise for the future study of both medicine and biology. However, the data generated is extremely intricate in its correlation structure, and its proper analysis is complex. There are issues with missing identifications. There are high levels of correlation between many, but not all, of the peptides derived from the same protein. Additionally, there may be systematic shifts in the sensitivity of the machine between experiments or even through time within the duration of a single experiment.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 57 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Croatia 1 2%
Russia 1 2%
South Africa 1 2%
Unknown 54 95%

Demographic breakdown

Readers by professional status Count As %
Researcher 14 25%
Student > Bachelor 14 25%
Student > Ph. D. Student 10 18%
Professor > Associate Professor 3 5%
Other 2 4%
Other 8 14%
Unknown 6 11%
Readers by discipline Count As %
Agricultural and Biological Sciences 22 39%
Biochemistry, Genetics and Molecular Biology 9 16%
Computer Science 5 9%
Engineering 3 5%
Medicine and Dentistry 3 5%
Other 8 14%
Unknown 7 12%