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MYOD-1 in normal colonic mucosa – role as a putative biomarker?

Overview of attention for article published in BMC Research Notes, May 2012
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Title
MYOD-1 in normal colonic mucosa – role as a putative biomarker?
Published in
BMC Research Notes, May 2012
DOI 10.1186/1756-0500-5-240
Pubmed ID
Authors

Ramesh P Arasaradnam, M Nabil Quraishi, Daniel Commane, John C Mathers, Mike Bradburn

Abstract

DNA methylation of promoter-associated CpG islands of certain genes may play a role in the development of colorectal cancer. The MYOD-1 gene which is a muscle differentiation gene has been showed to be significantly methylated in colorectal cancer which, is an age related event. However the role of this gene in the colonic mucosa is not understood and whether methylation occurs in subjects without colon cancer. In this study, we have determined the frequency of methylation of the MYOD-1 gene in normal colonic mucosa and investigated to see if this is associated with established colorectal cancer risk factors primarily ageing.

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 19 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 19 100%

Demographic breakdown

Readers by professional status Count As %
Student > Bachelor 3 16%
Researcher 3 16%
Lecturer > Senior Lecturer 2 11%
Student > Ph. D. Student 2 11%
Librarian 1 5%
Other 4 21%
Unknown 4 21%
Readers by discipline Count As %
Medicine and Dentistry 7 37%
Agricultural and Biological Sciences 3 16%
Nursing and Health Professions 2 11%
Unspecified 1 5%
Environmental Science 1 5%
Other 2 11%
Unknown 3 16%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 25 May 2012.
All research outputs
#15,243,549
of 22,665,794 outputs
Outputs from BMC Research Notes
#2,308
of 4,248 outputs
Outputs of similar age
#104,247
of 163,779 outputs
Outputs of similar age from BMC Research Notes
#41
of 65 outputs
Altmetric has tracked 22,665,794 research outputs across all sources so far. This one is in the 22nd percentile – i.e., 22% of other outputs scored the same or lower than it.
So far Altmetric has tracked 4,248 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 5.5. This one is in the 33rd percentile – i.e., 33% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 163,779 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 25th percentile – i.e., 25% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 65 others from the same source and published within six weeks on either side of this one. This one is in the 29th percentile – i.e., 29% of its contemporaries scored the same or lower than it.