@JLLanciego Despite careful planning, most drug candidates fail. Reasons for failure include poor solubility, undesirable side effects, poor biodistribution, prohibitive scale-up and manufacturing costs, market competition, and poor efficacy in early clini
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Pre-Clinical (2)- Preclinical studies can develop the best procedure for new drug scale-up; select the best formulation; determine the route, frequency, and duration of exposure; and ultimately support the intended clinical trial design. https://t.co/Cc3Me
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The basics of preclinical drug development for neurodegenerative disease indications https://t.co/svxGUwaEiM #bmcneurol
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Interesting stuff http://t.co/YgyAaOPS