Title |
Cloud computing for comparative genomics
|
---|---|
Published in |
BMC Bioinformatics, May 2010
|
DOI | 10.1186/1471-2105-11-259 |
Pubmed ID | |
Authors |
Dennis P Wall, Parul Kudtarkar, Vincent A Fusaro, Rimma Pivovarov, Prasad Patil, Peter J Tonellato |
Abstract |
Large comparative genomics studies and tools are becoming increasingly more compute-expensive as the number of available genome sequences continues to rise. The capacity and cost of local computing infrastructures are likely to become prohibitive with the increase, especially as the breadth of questions continues to rise. Alternative computing architectures, in particular cloud computing environments, may help alleviate this increasing pressure and enable fast, large-scale, and cost-effective comparative genomics strategies going forward. To test this, we redesigned a typical comparative genomics algorithm, the reciprocal smallest distance algorithm (RSD), to run within Amazon's Elastic Computing Cloud (EC2). We then employed the RSD-cloud for ortholog calculations across a wide selection of fully sequenced genomes. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
Spain | 1 | 50% |
United Kingdom | 1 | 50% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Practitioners (doctors, other healthcare professionals) | 1 | 50% |
Scientists | 1 | 50% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
United States | 10 | 5% |
Brazil | 5 | 3% |
Germany | 3 | 2% |
United Kingdom | 3 | 2% |
Spain | 2 | 1% |
India | 2 | 1% |
France | 1 | <1% |
Turkey | 1 | <1% |
Sweden | 1 | <1% |
Other | 11 | 6% |
Unknown | 155 | 80% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Ph. D. Student | 43 | 22% |
Researcher | 43 | 22% |
Student > Master | 27 | 14% |
Student > Bachelor | 16 | 8% |
Other | 11 | 6% |
Other | 44 | 23% |
Unknown | 10 | 5% |
Readers by discipline | Count | As % |
---|---|---|
Computer Science | 70 | 36% |
Agricultural and Biological Sciences | 70 | 36% |
Engineering | 9 | 5% |
Medicine and Dentistry | 6 | 3% |
Biochemistry, Genetics and Molecular Biology | 5 | 3% |
Other | 19 | 10% |
Unknown | 15 | 8% |