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The significance of glucose, insulin and potassium for immunology and oncology: a new model of immunity

Overview of attention for article published in Journal of Immune Based Therapies and Vaccines, August 2005
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (93rd percentile)

Mentioned by

news
1 news outlet
twitter
3 X users
facebook
1 Facebook page
video
1 YouTube creator

Citations

dimensions_citation
7 Dimensions

Readers on

mendeley
25 Mendeley
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Title
The significance of glucose, insulin and potassium for immunology and oncology: a new model of immunity
Published in
Journal of Immune Based Therapies and Vaccines, August 2005
DOI 10.1186/1476-8518-3-5
Pubmed ID
Authors

Albert F Hill, William J Polvino, Darcy B Wilson

Abstract

A recent development in critical care medicine makes it urgent that research into the effect of hormones on immunity be pursued aggressively. Studies have demonstrated a large reduction in mortality as a result of infusion with glucose, insulin and potassium. Our work in the oncology setting has led us to propose that the principal reason for such an effect is that GIK stimulates lymphocytes to proliferate and attack pathogens, sparing the patient the stress of infection. That suggestion is based on a new model of immunity that describes the effect of hormones on lymphocytes. We hypothesized that the application of glucose, insulin, thyroid and potassium would awaken inert tumor infiltrating lymphocytes to destroy the tumor.

X Demographics

X Demographics

The data shown below were collected from the profiles of 3 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 25 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 25 100%

Demographic breakdown

Readers by professional status Count As %
Researcher 6 24%
Student > Master 5 20%
Student > Postgraduate 3 12%
Student > Bachelor 2 8%
Lecturer 2 8%
Other 3 12%
Unknown 4 16%
Readers by discipline Count As %
Medicine and Dentistry 12 48%
Agricultural and Biological Sciences 4 16%
Psychology 1 4%
Computer Science 1 4%
Sports and Recreations 1 4%
Other 1 4%
Unknown 5 20%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 14. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 27 April 2023.
All research outputs
#2,320,837
of 23,622,736 outputs
Outputs from Journal of Immune Based Therapies and Vaccines
#4
of 32 outputs
Outputs of similar age
#3,803
of 58,934 outputs
Outputs of similar age from Journal of Immune Based Therapies and Vaccines
#2
of 3 outputs
Altmetric has tracked 23,622,736 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 90th percentile: it's in the top 10% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 32 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 14.6. This one scored the same or higher as 28 of them.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 58,934 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 93% of its contemporaries.
We're also able to compare this research output to 3 others from the same source and published within six weeks on either side of this one.