Title |
The significance of glucose, insulin and potassium for immunology and oncology: a new model of immunity
|
---|---|
Published in |
Journal of Immune Based Therapies and Vaccines, August 2005
|
DOI | 10.1186/1476-8518-3-5 |
Pubmed ID | |
Authors |
Albert F Hill, William J Polvino, Darcy B Wilson |
Abstract |
A recent development in critical care medicine makes it urgent that research into the effect of hormones on immunity be pursued aggressively. Studies have demonstrated a large reduction in mortality as a result of infusion with glucose, insulin and potassium. Our work in the oncology setting has led us to propose that the principal reason for such an effect is that GIK stimulates lymphocytes to proliferate and attack pathogens, sparing the patient the stress of infection. That suggestion is based on a new model of immunity that describes the effect of hormones on lymphocytes. We hypothesized that the application of glucose, insulin, thyroid and potassium would awaken inert tumor infiltrating lymphocytes to destroy the tumor. |
X Demographics
Geographical breakdown
Country | Count | As % |
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Comoros | 1 | 33% |
Unknown | 2 | 67% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 3 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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Unknown | 25 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
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Researcher | 6 | 24% |
Student > Master | 5 | 20% |
Student > Postgraduate | 3 | 12% |
Student > Bachelor | 2 | 8% |
Lecturer | 2 | 8% |
Other | 3 | 12% |
Unknown | 4 | 16% |
Readers by discipline | Count | As % |
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Medicine and Dentistry | 12 | 48% |
Agricultural and Biological Sciences | 4 | 16% |
Psychology | 1 | 4% |
Computer Science | 1 | 4% |
Sports and Recreations | 1 | 4% |
Other | 1 | 4% |
Unknown | 5 | 20% |