Title |
Integrating biological knowledge into variable selection: an empirical Bayes approach with an application in cancer biology
|
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Published in |
BMC Bioinformatics, May 2012
|
DOI | 10.1186/1471-2105-13-94 |
Pubmed ID | |
Authors |
Steven M Hill, Richard M Neve, Nora Bayani, Wen-Lin Kuo, Safiyyah Ziyad, Paul T Spellman, Joe W Gray, Sach Mukherjee |
Abstract |
An important question in the analysis of biochemical data is that of identifying subsets of molecular variables that may jointly influence a biological response. Statistical variable selection methods have been widely used for this purpose. In many settings, it may be important to incorporate ancillary biological information concerning the variables of interest. Pathway and network maps are one example of a source of such information. However, although ancillary information is increasingly available, it is not always clear how it should be used nor how it should be weighted in relation to primary data. |
X Demographics
Geographical breakdown
Country | Count | As % |
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United States | 1 | 100% |
Demographic breakdown
Type | Count | As % |
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Scientists | 1 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
United States | 3 | 4% |
United Kingdom | 2 | 3% |
Netherlands | 1 | 1% |
Ghana | 1 | 1% |
Switzerland | 1 | 1% |
Brazil | 1 | 1% |
Taiwan | 1 | 1% |
Canada | 1 | 1% |
Unknown | 66 | 86% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Ph. D. Student | 26 | 34% |
Researcher | 16 | 21% |
Student > Master | 10 | 13% |
Professor > Associate Professor | 6 | 8% |
Other | 4 | 5% |
Other | 10 | 13% |
Unknown | 5 | 6% |
Readers by discipline | Count | As % |
---|---|---|
Agricultural and Biological Sciences | 24 | 31% |
Computer Science | 11 | 14% |
Biochemistry, Genetics and Molecular Biology | 7 | 9% |
Medicine and Dentistry | 7 | 9% |
Engineering | 7 | 9% |
Other | 12 | 16% |
Unknown | 9 | 12% |