Title |
High risk HPV types 18 and 16 are potent modulators of oral squamous cell carcinoma phenotypes in vitro
|
---|---|
Published in |
Infectious Agents and Cancer, November 2007
|
DOI | 10.1186/1750-9378-2-21 |
Pubmed ID | |
Authors |
Nicole Reddout, Todd Christensen, Anthony Bunnell, Dayne Jensen, Devin Johnson, Susan O'Malley, Karl Kingsley |
Abstract |
Human papillomavirus (HPV) has been confirmed as the primary etiological factor that transforms cervical epithelia into cancer. The presence of HPV in oral cancers suggests that HPV may play a similar role in transforming the oral epithelia. A high degree of variability in the prevalence of HPV in oral cancers has been found, however, raising questions regarding its role in the transformation and development of oral cancers. The goal of this study was to test our hypothesis that high-risk HPV strains HPV16 and HPV18 will alter the phenotype of transformed oral squamous cell carcinoma cell lines, CAL27, SCC-15 and SCC-25 in vitro. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 1 | 100% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 1 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Colombia | 1 | 2% |
Unknown | 52 | 98% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Master | 11 | 21% |
Student > Bachelor | 10 | 19% |
Student > Ph. D. Student | 7 | 13% |
Student > Postgraduate | 5 | 9% |
Researcher | 3 | 6% |
Other | 9 | 17% |
Unknown | 8 | 15% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 26 | 49% |
Agricultural and Biological Sciences | 4 | 8% |
Immunology and Microbiology | 3 | 6% |
Social Sciences | 3 | 6% |
Engineering | 2 | 4% |
Other | 5 | 9% |
Unknown | 10 | 19% |