Title |
Hepatoprotective effects of Spirulina maxima in patients with non-alcoholic fatty liver disease: a case series
|
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Published in |
Journal of Medical Case Reports, April 2010
|
DOI | 10.1186/1752-1947-4-103 |
Pubmed ID | |
Authors |
Aldo Ferreira-Hermosillo, Patricia V Torres-Duran, Marco A Juarez-Oropeza |
Abstract |
Non-alcoholic fatty liver diseases range from simple steatosis to non-alcoholic steatohepatitis. The "two hits" hypothesis is widely accepted for its pathogenesis: the first hit is an increased fat flux to the liver, which predisposes our patient to a second hit where increasing free fatty acid oxidation into the mitochondria leads to oxidative stress, lipoperoxidation and a chain reaction with increased ROS. Clinical indications include abdominal cramps, meteorism and fatigue. Most patients, however, are asymptomatic, and diagnosis is based on aminotransferase elevation and ultrasonography (or "brilliant liver"). Spirulina maxima has been experimentally proven to possess in vivo and in vitro hepatoprotective properties by maintaining the liver lipid profile. This case report evaluates the hepatoprotective effects of orally supplied Spirulina maxima. |
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Geographical breakdown
Country | Count | As % |
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Spain | 2 | 29% |
United States | 1 | 14% |
Georgia | 1 | 14% |
Dominican Republic | 1 | 14% |
Malaysia | 1 | 14% |
Unknown | 1 | 14% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 5 | 71% |
Practitioners (doctors, other healthcare professionals) | 2 | 29% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Mexico | 1 | 1% |
India | 1 | 1% |
China | 1 | 1% |
Unknown | 86 | 97% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Master | 14 | 16% |
Student > Bachelor | 13 | 15% |
Researcher | 12 | 13% |
Student > Ph. D. Student | 9 | 10% |
Student > Doctoral Student | 8 | 9% |
Other | 20 | 22% |
Unknown | 13 | 15% |
Readers by discipline | Count | As % |
---|---|---|
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Medicine and Dentistry | 17 | 19% |
Biochemistry, Genetics and Molecular Biology | 9 | 10% |
Nursing and Health Professions | 5 | 6% |
Veterinary Science and Veterinary Medicine | 3 | 3% |
Other | 15 | 17% |
Unknown | 21 | 24% |