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The Drosophila Netrin receptor frazzled/DCC functions as an invasive tumor suppressor

Overview of attention for article published in BMC Developmental Biology, June 2011
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Title
The Drosophila Netrin receptor frazzled/DCC functions as an invasive tumor suppressor
Published in
BMC Developmental Biology, June 2011
DOI 10.1186/1471-213x-11-41
Pubmed ID
Authors

Adrienne VanZomeren-Dohm, Joseph Sarro, Ellen Flannery, Molly Duman-Scheel

Abstract

Loss of heterozygosity at 18q, which includes the Deleted in Colorectal Cancer (DCC) gene, has been linked to many human cancers. However, it is unclear if loss of DCC is the specific underlying cause of these cancers. The Drosophila imaginal discs are excellent systems in which to study DCC function, as it is possible to model human tumors through the generation of somatic clones of cells bearing multiple genetic lesions. Here, these attributes of the fly system were utilized to investigate the potential tumor suppressing functions of the Drosophila DCC homologue frazzled (fra) during eye-antennal disc development.

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X Demographics

The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 29 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 1 3%
Unknown 28 97%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 6 21%
Researcher 6 21%
Student > Bachelor 4 14%
Professor > Associate Professor 3 10%
Student > Master 3 10%
Other 4 14%
Unknown 3 10%
Readers by discipline Count As %
Agricultural and Biological Sciences 17 59%
Biochemistry, Genetics and Molecular Biology 4 14%
Neuroscience 3 10%
Medicine and Dentistry 2 7%
Unknown 3 10%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 29 May 2012.
All research outputs
#18,306,425
of 22,665,794 outputs
Outputs from BMC Developmental Biology
#304
of 369 outputs
Outputs of similar age
#96,111
of 113,614 outputs
Outputs of similar age from BMC Developmental Biology
#5
of 5 outputs
Altmetric has tracked 22,665,794 research outputs across all sources so far. This one is in the 11th percentile – i.e., 11% of other outputs scored the same or lower than it.
So far Altmetric has tracked 369 research outputs from this source. They receive a mean Attention Score of 4.3. This one is in the 9th percentile – i.e., 9% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 113,614 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 7th percentile – i.e., 7% of its contemporaries scored the same or lower than it.
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