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Functional Roles of Long Non-coding RNAs in Motor Neuron Development and Disease

Overview of attention for article published in Journal of Biomedical Science, February 2020
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (84th percentile)
  • High Attention Score compared to outputs of the same age and source (86th percentile)

Mentioned by

news
1 news outlet
twitter
7 X users

Citations

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26 Dimensions

Readers on

mendeley
79 Mendeley
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Title
Functional Roles of Long Non-coding RNAs in Motor Neuron Development and Disease
Published in
Journal of Biomedical Science, February 2020
DOI 10.1186/s12929-020-00628-z
Pubmed ID
Authors

Kuan-Wei Chen, Jun-An Chen

Abstract

Long non-coding RNAs (lncRNAs) have gained increasing attention as they exhibit highly tissue- and cell-type specific expression patterns. LncRNAs are highly expressed in the central nervous system and their roles in the brain have been studied intensively in recent years, but their roles in the spinal motor neurons (MNs) are largely unexplored. Spinal MN development is controlled by precise expression of a gene regulatory network mediated spatiotemporally by transcription factors, representing an elegant paradigm for deciphering the roles of lncRNAs during development. Moreover, many MN-related neurodegenerative diseases, such as amyotrophic lateral sclerosis (ALS) and spinal muscular atrophy (SMA), are associated with RNA metabolism, yet the link between MN-related diseases and lncRNAs remains obscure. In this review, we summarize lncRNAs known to be involved in MN development and disease, and discuss their potential future therapeutic applications.

X Demographics

X Demographics

The data shown below were collected from the profiles of 7 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 79 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 79 100%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 11 14%
Student > Master 11 14%
Researcher 9 11%
Student > Doctoral Student 7 9%
Student > Bachelor 7 9%
Other 8 10%
Unknown 26 33%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 21 27%
Neuroscience 18 23%
Agricultural and Biological Sciences 4 5%
Medicine and Dentistry 4 5%
Unspecified 2 3%
Other 5 6%
Unknown 25 32%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 14. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 14 August 2020.
All research outputs
#2,563,925
of 25,387,668 outputs
Outputs from Journal of Biomedical Science
#98
of 1,104 outputs
Outputs of similar age
#58,032
of 383,195 outputs
Outputs of similar age from Journal of Biomedical Science
#3
of 22 outputs
Altmetric has tracked 25,387,668 research outputs across all sources so far. Compared to these this one has done well and is in the 89th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 1,104 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 11.0. This one has done particularly well, scoring higher than 91% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 383,195 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 84% of its contemporaries.
We're also able to compare this research output to 22 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 86% of its contemporaries.