Title |
Transcripts with in silico predicted RNA structure are enriched everywhere in the mouse brain
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Published in |
BMC Genomics, May 2012
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DOI | 10.1186/1471-2164-13-214 |
Pubmed ID | |
Authors |
Stefan E Seemann, Susan M Sunkin, Michael J Hawrylycz, Walter L Ruzzo, Jan Gorodkin |
Abstract |
Post-transcriptional control of gene expression is mostly conducted by specific elements in untranslated regions (UTRs) of mRNAs, in collaboration with specific binding proteins and RNAs. In several well characterized cases, these RNA elements are known to form stable secondary structures. RNA secondary structures also may have major functional implications for long noncoding RNAs (lncRNAs). Recent transcriptional data has indicated the importance of lncRNAs in brain development and function. However, no methodical efforts to investigate this have been undertaken. Here, we aim to systematically analyze the potential for RNA structure in brain-expressed transcripts. |
X Demographics
Geographical breakdown
Country | Count | As % |
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France | 1 | 50% |
Unknown | 1 | 50% |
Demographic breakdown
Type | Count | As % |
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Scientists | 1 | 50% |
Members of the public | 1 | 50% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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United States | 3 | 7% |
Italy | 1 | 2% |
France | 1 | 2% |
Denmark | 1 | 2% |
Canada | 1 | 2% |
Unknown | 34 | 83% |
Demographic breakdown
Readers by professional status | Count | As % |
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Student > Ph. D. Student | 12 | 29% |
Researcher | 12 | 29% |
Student > Master | 3 | 7% |
Student > Bachelor | 2 | 5% |
Professor > Associate Professor | 2 | 5% |
Other | 5 | 12% |
Unknown | 5 | 12% |
Readers by discipline | Count | As % |
---|---|---|
Agricultural and Biological Sciences | 22 | 54% |
Biochemistry, Genetics and Molecular Biology | 7 | 17% |
Computer Science | 2 | 5% |
Neuroscience | 2 | 5% |
Medicine and Dentistry | 1 | 2% |
Other | 1 | 2% |
Unknown | 6 | 15% |