Title |
Role of plasma EBV DNA levels in predicting recurrence of nasopharyngeal carcinoma in a western population
|
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Published in |
BMC Cancer, May 2012
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DOI | 10.1186/1471-2407-12-208 |
Pubmed ID | |
Authors |
Daris Ferrari, Carla Codecà, Cecilia Bertuzzi, Francesca Broggio, Francesca Crepaldi, Andrea Luciani, Irene Floriani, Mohssen Ansarin, Fausto Chiesa, Daniela Alterio, Paolo Foa |
Abstract |
Loco-regionally advanced nasopharyngeal carcinomas can be cured by the combination of chemotherapy and radiotherapy. In Eastern countries, plasma levels of viral Epstein-Barr deoxyribonucleic acid (DNA) are accurate in predicting recurrence, but few data are available in Western populations. The aim of this prospective study was to evaluate the relationship between viral Epstein-Barr DNA copy numbers in plasma and the response rate, progression-free survival and overall survival in a cohort of Western patients with stage IIb-IVb nasopharyngeal cancer. |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Poland | 1 | 2% |
Unknown | 41 | 98% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Ph. D. Student | 7 | 17% |
Student > Bachelor | 6 | 14% |
Other | 5 | 12% |
Researcher | 4 | 10% |
Student > Postgraduate | 4 | 10% |
Other | 9 | 21% |
Unknown | 7 | 17% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 21 | 50% |
Biochemistry, Genetics and Molecular Biology | 3 | 7% |
Nursing and Health Professions | 2 | 5% |
Immunology and Microbiology | 2 | 5% |
Mathematics | 1 | 2% |
Other | 5 | 12% |
Unknown | 8 | 19% |