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Comparison of linear mixed model analysis and genealogy-based haplotype clustering with a Bayesian approach for association mapping in a pedigreed population

Overview of attention for article published in BMC Proceedings, May 2012
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Title
Comparison of linear mixed model analysis and genealogy-based haplotype clustering with a Bayesian approach for association mapping in a pedigreed population
Published in
BMC Proceedings, May 2012
DOI 10.1186/1753-6561-6-s2-s4
Pubmed ID
Authors

Golam R Dashab, Naveen K Kadri, Mohammad M Shariati, Goutam Sahana

Abstract

Despite many success stories of genome wide association studies (GWAS), challenges exist in QTL detection especially in datasets with many levels of relatedness. In this study we compared four methods of GWA on a dataset simulated for the 15th QTL-MAS workshop. The four methods were 1) Mixed model analysis (MMA), 2) Random haplotype model (RHM), 3) Genealogy-based mixed model (GENMIX), and 4) Bayesian variable selection (BVS). The data consisted of phenotypes of 2000 animals from 20 sire families and were genotyped with 9990 SNPs on five chromosomes.

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The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 34 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 34 100%

Demographic breakdown

Readers by professional status Count As %
Researcher 8 24%
Student > Ph. D. Student 7 21%
Professor > Associate Professor 3 9%
Student > Doctoral Student 3 9%
Student > Master 3 9%
Other 7 21%
Unknown 3 9%
Readers by discipline Count As %
Agricultural and Biological Sciences 20 59%
Physics and Astronomy 2 6%
Biochemistry, Genetics and Molecular Biology 2 6%
Business, Management and Accounting 1 3%
Mathematics 1 3%
Other 5 15%
Unknown 3 9%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 31 May 2012.
All research outputs
#18,308,895
of 22,668,244 outputs
Outputs from BMC Proceedings
#265
of 374 outputs
Outputs of similar age
#125,954
of 163,633 outputs
Outputs of similar age from BMC Proceedings
#10
of 16 outputs
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