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Effect of L-arginine supplement on liver regeneration after partial hepatectomy in rats

Overview of attention for article published in World Journal of Surgical Oncology, May 2012
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • Good Attention Score compared to outputs of the same age (76th percentile)
  • High Attention Score compared to outputs of the same age and source (97th percentile)

Mentioned by

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4 X users
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1 patent
googleplus
1 Google+ user

Citations

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21 Dimensions

Readers on

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25 Mendeley
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Title
Effect of L-arginine supplement on liver regeneration after partial hepatectomy in rats
Published in
World Journal of Surgical Oncology, May 2012
DOI 10.1186/1477-7819-10-99
Pubmed ID
Authors

Tsuyoshi Kurokawa, Jun An, Koji Tsunekawa, Yoshiharu Shimomura, Shunsuke Kazama, Naohisa Ishikawa, Toshiaki Nonami, Satoru Sugiyama

Abstract

Nitric oxide (NO) has been reported to be a key mediator in hepatocyte proliferation during liver regeneration. NO is the oxidative metabolite of L-arginine, and is produced by a family of enzymes, collective termed nitric oxide synthase (NOS). Thus, administration of L-arginine might enhance liver regeneration after a hepatectomy. Another amino acid, L-glutamine, which plays an important role in catabolic states and is a crucial factor in various cellular and organ functions, is widely known to enhance liver regeneration experimentally. Thus, the present study was undertaken to evaluate the effects of an L-arginine supplement on liver regeneration, and to compared this with supplementation with L-glutamine and L-alanine (the latter as a negative control), using a rat partial hepatectomy model.

X Demographics

X Demographics

The data shown below were collected from the profiles of 4 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 25 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Turkey 1 4%
Unknown 24 96%

Demographic breakdown

Readers by professional status Count As %
Researcher 5 20%
Student > Master 4 16%
Other 3 12%
Student > Bachelor 3 12%
Student > Ph. D. Student 3 12%
Other 2 8%
Unknown 5 20%
Readers by discipline Count As %
Medicine and Dentistry 5 20%
Agricultural and Biological Sciences 5 20%
Biochemistry, Genetics and Molecular Biology 4 16%
Chemistry 2 8%
Pharmacology, Toxicology and Pharmaceutical Science 1 4%
Other 1 4%
Unknown 7 28%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 6. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 11 December 2023.
All research outputs
#6,140,769
of 24,978,429 outputs
Outputs from World Journal of Surgical Oncology
#167
of 2,130 outputs
Outputs of similar age
#40,290
of 170,627 outputs
Outputs of similar age from World Journal of Surgical Oncology
#3
of 80 outputs
Altmetric has tracked 24,978,429 research outputs across all sources so far. Compared to these this one has done well and is in the 75th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 2,130 research outputs from this source. They receive a mean Attention Score of 2.2. This one has done particularly well, scoring higher than 92% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 170,627 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 76% of its contemporaries.
We're also able to compare this research output to 80 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 97% of its contemporaries.