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Over-expression of BMPR-IB reduces the malignancy of glioblastoma cells by upregulation of p21 and p27Kip1

Overview of attention for article published in Journal of Experimental & Clinical Cancer Research, May 2012
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Title
Over-expression of BMPR-IB reduces the malignancy of glioblastoma cells by upregulation of p21 and p27Kip1
Published in
Journal of Experimental & Clinical Cancer Research, May 2012
DOI 10.1186/1756-9966-31-52
Pubmed ID
Authors

Shuang Liu, Feng Yin, Wenhong Fan, Shuwei Wang, Xin-ru Guo, Jian-ning Zhang, Zeng-min Tian, Ming Fan

Abstract

In our previous study, we detected decreased expression of phospho-Smad1/5/8 and its upstream signaling molecule, bone morphogenetic protein receptor IB subunit (BMPR-IB), in certain glioblastoma tissues, unlike normal brain tissues. In order to clarify the functional roles and mechanism of BMPR-IB in the development of glioblastoma, we studied the effects of BMPR-IB overexpression on glioblastoma cell lines in vitro and in vivo.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 19 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Brazil 1 5%
Unknown 18 95%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 4 21%
Student > Doctoral Student 3 16%
Professor 3 16%
Student > Master 2 11%
Researcher 2 11%
Other 1 5%
Unknown 4 21%
Readers by discipline Count As %
Agricultural and Biological Sciences 7 37%
Biochemistry, Genetics and Molecular Biology 3 16%
Medicine and Dentistry 2 11%
Neuroscience 1 5%
Unknown 6 32%