Paper #1: https://t.co/6J68xcRJGk Highlights: 1) Better to use more guides per gene at a lower seq depth than fewer guides at a higher seq depth 2) Benchmarked the methods #MAGeCK_RRA, #MAGeCK_MLE, #CRISPhieRmix and #ttest 3) #MAGeCK_RRA should be used in
RT @BioDecoded: A benchmark of algorithms for the analysis of pooled CRISPR screens | Genome Biology https://t.co/Lqj32xjJ37 #Bioinformati…
Our new paper benchmarking algorithms for CRISPR screens, with design recommendations. Great collaboration with @stanleyqilab! https://t.co/rOuggxnJah
[REVIEW] A benchmark of algorithms for the analysis of pooled #CRISPR screens. Bodapati S [..] Qi LS. Genome Biol 2020-03-09. https://t.co/ST4IjW4MMi MAGeCK Robust Ranking Algorithm (RRA) MAGeCK maximum likelihood estimation (MLE) CRISPhieRmix JACKS CERES