Title |
Murine gammaherpesvirus 68 glycoprotein 150 does not contribute to latency amplification in vivo
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Published in |
Virology Journal, June 2012
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DOI | 10.1186/1743-422x-9-107 |
Pubmed ID | |
Authors |
Romana Ruiss, Shinji Ohno, Beatrix Steer, Reinhard Zeidler, Heiko Adler |
Abstract |
Murine gammaherpesvirus 68 (MHV-68) is used as a model to study the function of gammaherpesvirus glycoproteins. gp150 of MHV-68, encoded by open reading frame M7, is a positional homolog of gp350/220 of EBV and of gp35/37 of KSHV. Since it had been proposed that gp350/220 of EBV might be a suitable vaccine antigen to protect from EBV-associated diseases, gp150 has been applied as a model vaccine in the MHV-68 system. When analyzing the function of gp150, previous studies yielded conflicting results on the role of gp150 in latency amplification, and disparities between the mutant viruses which had been analyzed were blamed for the observed differences. |
X Demographics
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United States | 1 | 100% |
Demographic breakdown
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Members of the public | 1 | 100% |
Mendeley readers
Geographical breakdown
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Unknown | 24 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
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Student > Ph. D. Student | 8 | 33% |
Professor | 5 | 21% |
Researcher | 3 | 13% |
Professor > Associate Professor | 2 | 8% |
Student > Bachelor | 1 | 4% |
Other | 2 | 8% |
Unknown | 3 | 13% |
Readers by discipline | Count | As % |
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Medicine and Dentistry | 5 | 21% |
Biochemistry, Genetics and Molecular Biology | 2 | 8% |
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Psychology | 1 | 4% |
Other | 1 | 4% |
Unknown | 3 | 13% |