@mattwridley In mice there is good evidence for metabolic stress, like obesity, causing changes in imprinting and phenotype for offspring. And Russell silver syndrome is a human imprinting disease with a mouse model. https://t.co/DFKNNTwqK2 That seems lik
"Successful generation of epigenetic disease model mice by targeted demethylation of the epigenome" Horii T [..] Hatada I. Genome Biol. 2020-04-01. https://t.co/LK13xqUCpq
RT @GenomeBiology: Horii, Hatada and co use targeted demethylation to create a mouse model of the imprinting disorder Silver-Russell syndro…
RT @FrezzaLab: Successful generation of epigenetic disease model mice by targeted demethylation of the epigenome | Genome Biology | Full Te…