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Effects of high-fat diet and physical activity on pyruvate dehydrogenase kinase-4 in mouse skeletal muscle

Overview of attention for article published in Nutrition & Metabolism, June 2012
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4 X users

Citations

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42 Dimensions

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53 Mendeley
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Title
Effects of high-fat diet and physical activity on pyruvate dehydrogenase kinase-4 in mouse skeletal muscle
Published in
Nutrition & Metabolism, June 2012
DOI 10.1186/1743-7075-9-53
Pubmed ID
Authors

Rita Rinnankoski-Tuikka, Mika Silvennoinen, Sira Torvinen, Juha J Hulmi, Maarit Lehti, Riikka Kivelä, Hilkka Reunanen, Heikki Kainulainen

Abstract

The expression of PDK4 is elevated by diabetes, fasting and other conditions associated with the switch from the utilization of glucose to fatty acids as an energy source. It is previously shown that peroxisome proliferator-activated receptor γ coactivator 1α (PGC-1α), a master regulator of energy metabolism, coactivates in cell lines pyruvate dehydrogenase kinase-4 (PDK4) gene expression via the estrogen-related receptor α (ERRα). We investigated the effects of long-term high-fat diet and physical activity on the expression of PDK4, PGC-1α and ERRα and the amount and function of mitochondria in skeletal muscle.

X Demographics

X Demographics

The data shown below were collected from the profiles of 4 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 53 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Chile 1 2%
United States 1 2%
Unknown 51 96%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 9 17%
Student > Master 8 15%
Researcher 7 13%
Student > Bachelor 6 11%
Professor 4 8%
Other 8 15%
Unknown 11 21%
Readers by discipline Count As %
Agricultural and Biological Sciences 11 21%
Biochemistry, Genetics and Molecular Biology 10 19%
Sports and Recreations 5 9%
Medicine and Dentistry 5 9%
Nursing and Health Professions 3 6%
Other 8 15%
Unknown 11 21%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 3. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 15 June 2012.
All research outputs
#7,414,160
of 22,668,244 outputs
Outputs from Nutrition & Metabolism
#487
of 942 outputs
Outputs of similar age
#55,059
of 166,771 outputs
Outputs of similar age from Nutrition & Metabolism
#12
of 18 outputs
Altmetric has tracked 22,668,244 research outputs across all sources so far. This one is in the 44th percentile – i.e., 44% of other outputs scored the same or lower than it.
So far Altmetric has tracked 942 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 25.3. This one is in the 45th percentile – i.e., 45% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 166,771 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 47th percentile – i.e., 47% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 18 others from the same source and published within six weeks on either side of this one. This one is in the 33rd percentile – i.e., 33% of its contemporaries scored the same or lower than it.