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Matrix metalloproteinase 9 contributes to gut microbe homeostasis in a model of infectious colitis

Overview of attention for article published in BMC Microbiology, June 2012
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Title
Matrix metalloproteinase 9 contributes to gut microbe homeostasis in a model of infectious colitis
Published in
BMC Microbiology, June 2012
DOI 10.1186/1471-2180-12-105
Pubmed ID
Authors

David M Rodrigues, Andrew J Sousa, Steve P Hawley, Linda Vong, Melanie G Gareau, Sachin A Kumar, Kathene C Johnson-Henry, Philip M Sherman

Abstract

Inflammatory bowel diseases are associated with increased expression of zinc-dependent Matrix Metalloproteinase 9 (MMP-9). A stark dysregulation of intestinal mucosal homeostasis has been observed in patients with chronic inflammatory bowel diseases. We therefore sought to determine the contribution of MMP-9 to the pathogenesis of Citrobacter rodentium-induced colitis and its effects on gut microbiome homeostasis.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 62 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Canada 1 2%
Unknown 61 98%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 11 18%
Student > Master 10 16%
Researcher 9 15%
Student > Bachelor 6 10%
Student > Doctoral Student 5 8%
Other 6 10%
Unknown 15 24%
Readers by discipline Count As %
Agricultural and Biological Sciences 23 37%
Medicine and Dentistry 9 15%
Immunology and Microbiology 5 8%
Biochemistry, Genetics and Molecular Biology 3 5%
Veterinary Science and Veterinary Medicine 1 2%
Other 4 6%
Unknown 17 27%