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A retrospective pooled analysis of response patterns and risk factors in recurrent malignant glioma patients receiving a nitrosourea-based chemotherapy

Overview of attention for article published in Journal of Translational Medicine, May 2012
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Title
A retrospective pooled analysis of response patterns and risk factors in recurrent malignant glioma patients receiving a nitrosourea-based chemotherapy
Published in
Journal of Translational Medicine, May 2012
DOI 10.1186/1479-5876-10-90
Pubmed ID
Authors

Alessandro Paccapelo, Ivan Lolli, Maria Grazia Fabrini, Giovanni Silvano, Beatrice Detti, Franco Perrone, Giuseppina Savio, Matteo Santoni, Erminio Bonizzoni, Tania Perrone, Silvia Scoccianti

Abstract

At recurrence the use of nitrosoureas is widely-used as a therapeutic option for glioblastoma (GBM) patients. The efficacy of fotemustine (FTM) has been demonstrated in phase II clinical trials; however, these papers report a wide range of progression-free-survival (PFS-6 m) rates, ranging from 21% to 52%. We investigated whether FTM could have a different response pattern in respect to time to adjuvant temozolomide failure, or whether specific independent risk factors could be responsible for the wide range of response rates observed.

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X Demographics

The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 22 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United Kingdom 1 5%
Unknown 21 95%

Demographic breakdown

Readers by professional status Count As %
Student > Bachelor 4 18%
Researcher 4 18%
Student > Doctoral Student 3 14%
Student > Master 3 14%
Student > Ph. D. Student 2 9%
Other 2 9%
Unknown 4 18%
Readers by discipline Count As %
Medicine and Dentistry 12 55%
Neuroscience 2 9%
Agricultural and Biological Sciences 1 5%
Psychology 1 5%
Nursing and Health Professions 1 5%
Other 0 0%
Unknown 5 23%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 15 June 2012.
All research outputs
#18,308,895
of 22,668,244 outputs
Outputs from Journal of Translational Medicine
#2,925
of 3,954 outputs
Outputs of similar age
#126,299
of 163,897 outputs
Outputs of similar age from Journal of Translational Medicine
#34
of 62 outputs
Altmetric has tracked 22,668,244 research outputs across all sources so far. This one is in the 11th percentile – i.e., 11% of other outputs scored the same or lower than it.
So far Altmetric has tracked 3,954 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 10.5. This one is in the 16th percentile – i.e., 16% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 163,897 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 9th percentile – i.e., 9% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 62 others from the same source and published within six weeks on either side of this one. This one is in the 3rd percentile – i.e., 3% of its contemporaries scored the same or lower than it.