Title |
N-terminal pro-brain natriuretic peptide in a novel screening algorithm for pulmonary arterial hypertension in systemic sclerosis: a case-control study
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Published in |
Arthritis Research & Therapy, June 2012
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DOI | 10.1186/ar3876 |
Pubmed ID | |
Authors |
Vivek Thakkar, Wendy M Stevens, David Prior, Owen A Moore, Jillian Byron, Danny Liew, Karen Patterson, Pravin Hissaria, Janet Roddy, Jane Zochling, Joanne Sahhar, Peter Nash, Kathleen Tymms, David Celermajer, Eli Gabbay, Peter Youssef, Susanna M Proudman, Mandana Nikpour |
Abstract |
Pulmonary arterial hypertension is a major cause of mortality in systemic sclerosis. N-terminal pro-brain natriuretic peptide (NT-proBNP) has emerged as a candidate biomarker that may enable the early detection of systemic sclerosis-related pulmonary arterial hypertension (SSc-PAH). The objective of our study was to incorporate NT-proBNP into a screening algorithm for SSc-PAH that could potentially replace transthoracic echocardiography (TTE) as a more convenient and less costly "first tier" test. |
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Country | Count | As % |
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United Kingdom | 1 | 50% |
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Members of the public | 2 | 100% |
Mendeley readers
Geographical breakdown
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Germany | 1 | 1% |
Unknown | 77 | 96% |
Demographic breakdown
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Researcher | 9 | 11% |
Student > Bachelor | 8 | 10% |
Student > Ph. D. Student | 7 | 9% |
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Unknown | 20 | 25% |
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Engineering | 2 | 3% |
Other | 5 | 6% |
Unknown | 28 | 35% |