↓ Skip to main content

Gene expression changes as markers of early lapatinib response in a panel of breast cancer cell lines

Overview of attention for article published in Molecular Cancer, June 2012
Altmetric Badge

Mentioned by

twitter
1 X user

Citations

dimensions_citation
24 Dimensions

Readers on

mendeley
55 Mendeley
citeulike
1 CiteULike
You are seeing a free-to-access but limited selection of the activity Altmetric has collected about this research output. Click here to find out more.
Title
Gene expression changes as markers of early lapatinib response in a panel of breast cancer cell lines
Published in
Molecular Cancer, June 2012
DOI 10.1186/1476-4598-11-41
Pubmed ID
Authors

Fiona O’Neill, Stephen F Madden, Sinead T Aherne, Martin Clynes, John Crown, Padraig Doolan, Robert O’Connor

Abstract

Lapatinib, a tyrosine kinase inhibitor of HER2 and EGFR and is approved, in combination with capecitabine, for the treatment of trastuzumab-refractory metastatic breast cancer. In order to establish a possible gene expression response to lapatinib, a panel of breast cancer cell lines with varying sensitivity to lapatinib were analysed using a combination of microarray and qPCR profiling.

X Demographics

X Demographics

The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 55 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Malaysia 1 2%
Unknown 54 98%

Demographic breakdown

Readers by professional status Count As %
Researcher 12 22%
Student > Ph. D. Student 8 15%
Student > Bachelor 7 13%
Student > Doctoral Student 4 7%
Student > Postgraduate 4 7%
Other 10 18%
Unknown 10 18%
Readers by discipline Count As %
Agricultural and Biological Sciences 17 31%
Medicine and Dentistry 8 15%
Biochemistry, Genetics and Molecular Biology 7 13%
Pharmacology, Toxicology and Pharmaceutical Science 4 7%
Psychology 3 5%
Other 8 15%
Unknown 8 15%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 21 June 2012.
All research outputs
#15,245,883
of 22,668,244 outputs
Outputs from Molecular Cancer
#1,037
of 1,713 outputs
Outputs of similar age
#104,729
of 164,521 outputs
Outputs of similar age from Molecular Cancer
#7
of 11 outputs
Altmetric has tracked 22,668,244 research outputs across all sources so far. This one is in the 22nd percentile – i.e., 22% of other outputs scored the same or lower than it.
So far Altmetric has tracked 1,713 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 5.7. This one is in the 30th percentile – i.e., 30% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 164,521 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 26th percentile – i.e., 26% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 11 others from the same source and published within six weeks on either side of this one. This one is in the 27th percentile – i.e., 27% of its contemporaries scored the same or lower than it.