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X Demographics
Mendeley readers
| Title |
A carboxylesterase, Esterase-6, modulates sensory physiological and behavioral response dynamics to pheromone in Drosophila
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|---|---|
| Published in |
BMC Biology, June 2012
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| DOI | 10.1186/1741-7007-10-56 |
| Pubmed ID | |
| Authors |
Thomas Chertemps, Adrien François, Nicolas Durand, Gloria Rosell, Teun Dekker, Philippe Lucas, Martine Maïbèche-Coisne |
| Abstract |
Insects respond to the spatial and temporal dynamics of a pheromone plume, which implies not only a strong response to 'odor on', but also to 'odor off'. This requires mechanisms geared toward a fast signal termination. Several mechanisms may contribute to signal termination, among which odorant-degrading enzymes. These enzymes putatively play a role in signal dynamics by a rapid inactivation of odorants in the vicinity of the sensory receptors, although direct in vivo experimental evidences are lacking. Here we verified the role of an extracellular carboxylesterase, esterase-6 (Est-6), in the sensory physiological and behavioral dynamics of Drosophila melanogaster response to its pheromone, cis-vaccenyl acetate (cVA). Est-6 was previously linked to post-mating effects in the reproductive system of females. As Est-6 is also known to hydrolyze cVA in vitro and is expressed in the main olfactory organ, the antenna, we tested here its role in olfaction as a putative odorant-degrading enzyme. |
X Demographics
The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 1 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Science communicators (journalists, bloggers, editors) | 1 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 93 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Canada | 2 | 2% |
| France | 1 | 1% |
| Germany | 1 | 1% |
| Kenya | 1 | 1% |
| United States | 1 | 1% |
| Unknown | 87 | 94% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Researcher | 19 | 20% |
| Student > Ph. D. Student | 17 | 18% |
| Student > Master | 14 | 15% |
| Student > Doctoral Student | 9 | 10% |
| Student > Bachelor | 7 | 8% |
| Other | 14 | 15% |
| Unknown | 13 | 14% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 53 | 57% |
| Biochemistry, Genetics and Molecular Biology | 10 | 11% |
| Chemistry | 4 | 4% |
| Nursing and Health Professions | 2 | 2% |
| Environmental Science | 2 | 2% |
| Other | 7 | 8% |
| Unknown | 15 | 16% |