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Rapid genome-scale mapping of chromatin accessibility in tissue

Overview of attention for article published in Epigenetics & Chromatin, June 2012
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (89th percentile)
  • Good Attention Score compared to outputs of the same age and source (66th percentile)

Mentioned by

blogs
1 blog
twitter
3 X users
patent
1 patent

Citations

dimensions_citation
31 Dimensions

Readers on

mendeley
88 Mendeley
citeulike
3 CiteULike
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Title
Rapid genome-scale mapping of chromatin accessibility in tissue
Published in
Epigenetics & Chromatin, June 2012
DOI 10.1186/1756-8935-5-10
Pubmed ID
Authors

Lars Grøntved, Russell Bandle, Sam John, Songjoon Baek, Hye-Jung Chung, Ying Liu, Greti Aguilera, Carl Oberholtzer, Gordon L Hager, David Levens

Abstract

The challenge in extracting genome-wide chromatin features from limiting clinical samples poses a significant hurdle in identification of regulatory marks that impact the physiological or pathological state. Current methods that identify nuclease accessible chromatin are reliant on large amounts of purified nuclei as starting material. This complicates analysis of trace clinical tissue samples that are often stored frozen. We have developed an alternative nuclease based procedure to bypass nuclear preparation to interrogate nuclease accessible regions in frozen tissue samples.

X Demographics

X Demographics

The data shown below were collected from the profiles of 3 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 88 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 4 5%
Portugal 1 1%
Denmark 1 1%
Germany 1 1%
Unknown 81 92%

Demographic breakdown

Readers by professional status Count As %
Researcher 40 45%
Student > Ph. D. Student 21 24%
Professor > Associate Professor 5 6%
Student > Bachelor 3 3%
Other 3 3%
Other 10 11%
Unknown 6 7%
Readers by discipline Count As %
Agricultural and Biological Sciences 51 58%
Biochemistry, Genetics and Molecular Biology 26 30%
Medicine and Dentistry 4 5%
Computer Science 2 2%
Unknown 5 6%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 12. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 05 January 2023.
All research outputs
#2,697,431
of 23,485,296 outputs
Outputs from Epigenetics & Chromatin
#88
of 573 outputs
Outputs of similar age
#17,710
of 165,755 outputs
Outputs of similar age from Epigenetics & Chromatin
#2
of 6 outputs
Altmetric has tracked 23,485,296 research outputs across all sources so far. Compared to these this one has done well and is in the 88th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 573 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 6.7. This one has done well, scoring higher than 84% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 165,755 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 89% of its contemporaries.
We're also able to compare this research output to 6 others from the same source and published within six weeks on either side of this one. This one has scored higher than 4 of them.