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May toxicity of amiodarone be prevented by antioxidants? A cell-culture study

Overview of attention for article published in Journal of Cardiothoracic Surgery, June 2012
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Title
May toxicity of amiodarone be prevented by antioxidants? A cell-culture study
Published in
Journal of Cardiothoracic Surgery, June 2012
DOI 10.1186/1749-8090-7-61
Pubmed ID
Authors

Ahmet Baris Durukan, Beril Erdem, Elif Durukan, Handan Sevim, Tugce Karaduman, Hasan Alper Gurbuz, Aylin Gurpinar, Cem Yorgancioglu

Abstract

Atrial Fibrillation is the most common arrhythmia encountered following cardiac surgery. The most commonly administered drug used in treatment and prophylaxis is amiodarone which has several toxic effects on major organ functions. There are few clinical data concerning prevention of toxic effects and there is no routinely suggested agent. The aim of this study is to document the cytotoxic effects of amiodarone on cell culture media and compare the cytoprotective effects of commonly used antioxidant agents.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 29 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Germany 1 3%
Unknown 28 97%

Demographic breakdown

Readers by professional status Count As %
Researcher 6 21%
Student > Master 6 21%
Student > Ph. D. Student 5 17%
Professor > Associate Professor 2 7%
Student > Postgraduate 2 7%
Other 0 0%
Unknown 8 28%
Readers by discipline Count As %
Medicine and Dentistry 7 24%
Agricultural and Biological Sciences 6 21%
Biochemistry, Genetics and Molecular Biology 5 17%
Pharmacology, Toxicology and Pharmaceutical Science 2 7%
Materials Science 1 3%
Other 0 0%
Unknown 8 28%