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A systems biology approach reveals common metastatic pathways in osteosarcoma

Overview of attention for article published in BMC Systems Biology, May 2012
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Title
A systems biology approach reveals common metastatic pathways in osteosarcoma
Published in
BMC Systems Biology, May 2012
DOI 10.1186/1752-0509-6-50
Pubmed ID
Authors

Ricardo J Flores, Yiting Li, Alexander Yu, Jianhe Shen, Pulivarthi H Rao, Serrine S Lau, Marina Vannucci, Ching C Lau, Tsz-Kwong Man

Abstract

Osteosarcoma (OS) is the most common malignant bone tumor in children and adolescents. The survival rate of patients with metastatic disease remains very dismal. Nevertheless, metastasis is a complex process and a single-level analysis is not likely to identify its key biological determinants. In this study, we used a systems biology approach to identify common metastatic pathways that are jointly supported by both mRNA and protein expression data in two distinct human metastatic OS models.

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The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 67 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United Kingdom 2 3%
United States 2 3%
Portugal 1 1%
India 1 1%
Italy 1 1%
Taiwan 1 1%
Brazil 1 1%
Unknown 58 87%

Demographic breakdown

Readers by professional status Count As %
Researcher 20 30%
Student > Ph. D. Student 16 24%
Student > Master 6 9%
Other 5 7%
Student > Postgraduate 4 6%
Other 11 16%
Unknown 5 7%
Readers by discipline Count As %
Agricultural and Biological Sciences 23 34%
Medicine and Dentistry 20 30%
Biochemistry, Genetics and Molecular Biology 7 10%
Chemistry 2 3%
Materials Science 2 3%
Other 6 9%
Unknown 7 10%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 06 July 2012.
All research outputs
#20,160,460
of 22,669,724 outputs
Outputs from BMC Systems Biology
#1,010
of 1,142 outputs
Outputs of similar age
#149,115
of 165,041 outputs
Outputs of similar age from BMC Systems Biology
#28
of 28 outputs
Altmetric has tracked 22,669,724 research outputs across all sources so far. This one is in the 1st percentile – i.e., 1% of other outputs scored the same or lower than it.
So far Altmetric has tracked 1,142 research outputs from this source. They receive a mean Attention Score of 3.6. This one is in the 1st percentile – i.e., 1% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 165,041 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 28 others from the same source and published within six weeks on either side of this one. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.