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Peripheral T-cell Lymphoma with Cyclin D1 overexpression: a case report

Overview of attention for article published in Diagnostic Pathology, July 2012
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Title
Peripheral T-cell Lymphoma with Cyclin D1 overexpression: a case report
Published in
Diagnostic Pathology, July 2012
DOI 10.1186/1746-1596-7-79
Pubmed ID
Authors

Gabriella Aquino, Renato Franco, Fioravante Ronconi, Annamaria Anniciello, Luigi Russo, Annarosaria De Chiara, Luigi Panico

Abstract

Peripheral T-cell lymphomas not otherwise specified are generally considered aggressive non-Hodgkin lymphomas, because of poor natural outcome and response to therapy. They show a complex karyotype without any specific genetic hallmark. We report a case of peripheral T-cell lymphoma not otherwise specified with heterogeneous nuclear cyclin D1 immunohistochemical overexpression, due to gene copy gain, a phenomenon similar to that observed in mantle cell lymphoma characterized by t(11;14)(q13;q32). In this case report we underline the diagnostic pitfall represented by cyclin D1 immunohistochemical overexpression in a T-cell lymphoma. Several pitfalls could lead to misinterpretation of diagnosis, therefore, we underlined the need to integrate the classical histology and immunohistochemistry with molecular tests as clonality or fluorescence in situ hybridization.

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The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 8 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 8 100%

Demographic breakdown

Readers by professional status Count As %
Student > Doctoral Student 1 13%
Student > Master 1 13%
Researcher 1 13%
Professor > Associate Professor 1 13%
Student > Postgraduate 1 13%
Other 0 0%
Unknown 3 38%
Readers by discipline Count As %
Medicine and Dentistry 3 38%
Computer Science 1 13%
Unknown 4 50%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 06 July 2012.
All research outputs
#18,309,495
of 22,669,724 outputs
Outputs from Diagnostic Pathology
#755
of 1,118 outputs
Outputs of similar age
#126,487
of 164,297 outputs
Outputs of similar age from Diagnostic Pathology
#15
of 22 outputs
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