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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Hepatitis Associated Aplastic Anemia: A review
|
|---|---|
| Published in |
Virology Journal, February 2011
|
| DOI | 10.1186/1743-422x-8-87 |
| Pubmed ID | |
| Authors |
Bisma Rauff, Muhammad Idrees, Shahida Amjad Riaz Shah, Sadia Butt, Azeem M Butt, Liaqat Ali, Abrar Hussain, Irshad-ur-Rehman, Muhammad Ali |
| Abstract |
Hepatitis-associated aplastic anemia (HAAA) is an uncommon but distinct variant of aplastic anemia in which pancytopenia appears two to three months after an acute attack of hepatitis. HAAA occurs most frequently in young male children and is lethal if leave untreated. The etiology of this syndrome is proposed to be attributed to various hepatitis and non hepatitis viruses. Several hepatitis viruses such as HAV, HBV, HCV, HDV, HEV and HGV have been associated with this set of symptoms. Viruses other than the hepatitis viruses such as parvovirus B19, Cytomegalovirus, Epstein bar virus, Transfusion Transmitted virus (TTV) and non-A-E hepatitis virus (unknown viruses) has also been documented to develop the syndrome. Considerable evidences including the clinical features, severe imbalance of the T cell immune system and effective response to immunosuppressive therapy strongly present HAAA as an immune mediated mechanism. However, no association of HAAA has been found with blood transfusions, drugs and toxins. Besides hepatitis and non hepatitis viruses and immunopathogenesis phenomenon as causative agents of the disorder, telomerase mutation, a genetic factor has also been predisposed for the development of aplastic anemia. Diagnosis includes clinical manifestations, blood profiling, viral serological markers testing, immune functioning and bone marrow hypocellularity examination. Patients presenting the features of HAAA have been mostly treated with bone marrow or hematopoietic cell transplantation from HLA matched donor, and if not available then by immunosuppressive therapy. New therapeutic approaches involve the administration of steroids especially the glucocorticoids to augment the immunosuppressive therapy response. Pancytopenia following an episode of acute hepatitis response better to hematopoietic cell transplantation than immunosuppressive therapy. |
X Demographics
The data shown below were collected from the profiles of 20 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Spain | 5 | 25% |
| Peru | 1 | 5% |
| Japan | 1 | 5% |
| Malaysia | 1 | 5% |
| Colombia | 1 | 5% |
| Unknown | 11 | 55% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 18 | 90% |
| Practitioners (doctors, other healthcare professionals) | 2 | 10% |
Mendeley readers
The data shown below were compiled from readership statistics for 161 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Czechia | 1 | <1% |
| Australia | 1 | <1% |
| Brazil | 1 | <1% |
| Unknown | 158 | 98% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 21 | 13% |
| Student > Master | 19 | 12% |
| Other | 18 | 11% |
| Student > Bachelor | 18 | 11% |
| Researcher | 16 | 10% |
| Other | 44 | 27% |
| Unknown | 25 | 16% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 79 | 49% |
| Agricultural and Biological Sciences | 16 | 10% |
| Immunology and Microbiology | 9 | 6% |
| Biochemistry, Genetics and Molecular Biology | 8 | 5% |
| Chemistry | 4 | 2% |
| Other | 15 | 9% |
| Unknown | 30 | 19% |
Attention Score in Context
This research output has an Altmetric Attention Score of 12. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 14 May 2022.
All research outputs
#2,828,467
of 24,332,257 outputs
Outputs from Virology Journal
#254
of 3,233 outputs
Outputs of similar age
#12,445
of 112,041 outputs
Outputs of similar age from Virology Journal
#5
of 51 outputs
Altmetric has tracked 24,332,257 research outputs across all sources so far. Compared to these this one has done well and is in the 88th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 3,233 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 25.1. This one has done particularly well, scoring higher than 92% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 112,041 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 88% of its contemporaries.
We're also able to compare this research output to 51 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 90% of its contemporaries.