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Stereotactic iodine-125 brachytherapy for brain tumors: temporary versus permanent implantation

Overview of attention for article published in Radiation Oncology, June 2012
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Title
Stereotactic iodine-125 brachytherapy for brain tumors: temporary versus permanent implantation
Published in
Radiation Oncology, June 2012
DOI 10.1186/1748-717x-7-94
Pubmed ID
Authors

Maximilian I Ruge, Philipp Kickingereder, Stefan Grau, Harald Treuer, Volker Sturm, Juergen Voges

Abstract

Stereotactic brachytherapy (SBT) has been described in several publications as an effective, minimal invasive and safe highly focal treatment option in selected patients with well circumscribed brain tumors <4 cm. However, a still ongoing discussion about indications and technique is hindering the definition of a clear legitimation of SBT in modern brain tumor treatment. These controversies encompass the question of how intense the irradiation should be delivered into the target volume (dose rate). For instance, reports about the use of high does rate (HDR) implantation schemes (>40 cGy/h) in combination with adjuvant external beam radiation and/or chemotherapy for the treatment of malignant gliomas and metastases resulted in increased rates of radiation induced adverse tissue changes requiring surgical intervention. Vice versa, such effects have been only minimally observed in numerous studies applying low dose rate (LDR) regiments (3-8 cGy/h) for low grade gliomas, metastases and other rare indications. Besides these observations, there are, however, no data available directly comparing the long term incidences of tissue changes after HDR and LDR and there is, furthermore, no evidence regarding a difference between temporary or permanent LDR implantation schemes. Thus, recommendations for effective and safe implantation schemes have to be investigated and compared in future studies.

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The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 27 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Nepal 1 4%
Unknown 26 96%

Demographic breakdown

Readers by professional status Count As %
Student > Doctoral Student 5 19%
Student > Postgraduate 4 15%
Student > Ph. D. Student 4 15%
Student > Bachelor 3 11%
Student > Master 2 7%
Other 3 11%
Unknown 6 22%
Readers by discipline Count As %
Medicine and Dentistry 11 41%
Veterinary Science and Veterinary Medicine 2 7%
Nursing and Health Professions 2 7%
Arts and Humanities 1 4%
Agricultural and Biological Sciences 1 4%
Other 3 11%
Unknown 7 26%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 08 July 2012.
All research outputs
#15,246,403
of 22,669,724 outputs
Outputs from Radiation Oncology
#1,036
of 2,044 outputs
Outputs of similar age
#104,677
of 164,469 outputs
Outputs of similar age from Radiation Oncology
#12
of 31 outputs
Altmetric has tracked 22,669,724 research outputs across all sources so far. This one is in the 22nd percentile – i.e., 22% of other outputs scored the same or lower than it.
So far Altmetric has tracked 2,044 research outputs from this source. They receive a mean Attention Score of 2.7. This one is in the 37th percentile – i.e., 37% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 164,469 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 26th percentile – i.e., 26% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 31 others from the same source and published within six weeks on either side of this one. This one is in the 41st percentile – i.e., 41% of its contemporaries scored the same or lower than it.