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Inflammation in Alzheimer's disease: relevance to pathogenesis and therapy

Overview of attention for article published in Alzheimer's Research & Therapy, January 2010
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (95th percentile)

Mentioned by

blogs
2 blogs
twitter
3 X users
patent
6 patents

Citations

dimensions_citation
191 Dimensions

Readers on

mendeley
239 Mendeley
citeulike
2 CiteULike
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Title
Inflammation in Alzheimer's disease: relevance to pathogenesis and therapy
Published in
Alzheimer's Research & Therapy, January 2010
DOI 10.1186/alzrt24
Pubmed ID
Authors

Elina Zotova, James AR Nicoll, Raj Kalaria, Clive Holmes, Delphine Boche

Abstract

Evidence for the involvement of inflammatory processes in the pathogenesis of Alzheimer's disease (AD) has been documented for a long time. However, the inflammation hypothesis in relation to AD pathology has emerged relatively recently. Even in this hypothesis, the inflammatory reaction is still considered to be a downstream effect of the accumulated proteins (amyloid beta (Abeta) and tau). This review aims to highlight the importance of the immune processes involved in AD pathogenesis based on the outcomes of the two major inflammation-relevant treatment strategies against AD developed and tested to date in animal studies and human clinical trials - the use of anti-inflammatory drugs and immunisation against Abeta.

X Demographics

X Demographics

The data shown below were collected from the profiles of 3 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 239 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United Kingdom 3 1%
Portugal 1 <1%
Netherlands 1 <1%
Greece 1 <1%
United States 1 <1%
Luxembourg 1 <1%
Poland 1 <1%
Unknown 230 96%

Demographic breakdown

Readers by professional status Count As %
Student > Master 39 16%
Student > Ph. D. Student 35 15%
Student > Bachelor 34 14%
Researcher 32 13%
Student > Doctoral Student 14 6%
Other 43 18%
Unknown 42 18%
Readers by discipline Count As %
Agricultural and Biological Sciences 47 20%
Medicine and Dentistry 38 16%
Neuroscience 36 15%
Biochemistry, Genetics and Molecular Biology 17 7%
Pharmacology, Toxicology and Pharmaceutical Science 15 6%
Other 35 15%
Unknown 51 21%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 22. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 08 September 2020.
All research outputs
#1,710,533
of 25,374,917 outputs
Outputs from Alzheimer's Research & Therapy
#272
of 1,465 outputs
Outputs of similar age
#7,602
of 172,437 outputs
Outputs of similar age from Alzheimer's Research & Therapy
#1
of 1 outputs
Altmetric has tracked 25,374,917 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 93rd percentile: it's in the top 10% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 1,465 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 26.6. This one has done well, scoring higher than 81% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 172,437 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 95% of its contemporaries.
We're also able to compare this research output to 1 others from the same source and published within six weeks on either side of this one. This one has scored higher than all of them