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Mesenchymal stem cell therapy in the treatment of osteoarthritis: reparative pathways, safety and efficacy – a review

Overview of attention for article published in BMC Musculoskeletal Disorders, May 2016
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (92nd percentile)
  • High Attention Score compared to outputs of the same age and source (92nd percentile)

Mentioned by

news
1 news outlet
blogs
1 blog
twitter
7 X users
facebook
1 Facebook page
wikipedia
1 Wikipedia page
googleplus
2 Google+ users

Citations

dimensions_citation
220 Dimensions

Readers on

mendeley
446 Mendeley
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Title
Mesenchymal stem cell therapy in the treatment of osteoarthritis: reparative pathways, safety and efficacy – a review
Published in
BMC Musculoskeletal Disorders, May 2016
DOI 10.1186/s12891-016-1085-9
Pubmed ID
Authors

Julien Freitag, Dan Bates, Richard Boyd, Kiran Shah, Adele Barnard, Leesa Huguenin, Abi Tenen

Abstract

Osteoarthritis is a leading cause of pain and disability across the world. With an aging population its prevalence is likely to further increase. Current accepted medical treatment strategies are aimed at symptom control rather than disease modification. Surgical options including joint replacement are not without possible significant complications. A growing interest in the area of regenerative medicine, led by an improved understanding of the role of mesenchymal stem cells in tissue homeostasis and repair, has seen recent focused efforts to explore the potential of stem cell therapies in the active management of symptomatic osteoarthritis. Encouragingly, results of pre-clinical and clinical trials have provided initial evidence of efficacy and indicated safety in the therapeutic use of mesenchymal stem cell therapies for the treatment of knee osteoarthritis. This paper explores the pathogenesis of osteoarthritis and how mesenchymal stem cells may play a role in future management strategies of this disabling condition.

X Demographics

X Demographics

The data shown below were collected from the profiles of 7 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 446 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 2 <1%
United Kingdom 1 <1%
Spain 1 <1%
Denmark 1 <1%
Unknown 441 99%

Demographic breakdown

Readers by professional status Count As %
Student > Bachelor 68 15%
Researcher 58 13%
Student > Master 55 12%
Student > Ph. D. Student 43 10%
Student > Doctoral Student 28 6%
Other 75 17%
Unknown 119 27%
Readers by discipline Count As %
Medicine and Dentistry 103 23%
Biochemistry, Genetics and Molecular Biology 62 14%
Agricultural and Biological Sciences 44 10%
Engineering 23 5%
Pharmacology, Toxicology and Pharmaceutical Science 16 4%
Other 70 16%
Unknown 128 29%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 26. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 09 June 2023.
All research outputs
#1,344,829
of 23,973,980 outputs
Outputs from BMC Musculoskeletal Disorders
#249
of 4,213 outputs
Outputs of similar age
#25,487
of 341,366 outputs
Outputs of similar age from BMC Musculoskeletal Disorders
#7
of 77 outputs
Altmetric has tracked 23,973,980 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 94th percentile: it's in the top 10% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 4,213 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 7.3. This one has done particularly well, scoring higher than 94% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 341,366 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 92% of its contemporaries.
We're also able to compare this research output to 77 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 92% of its contemporaries.