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A multi-task graph-clustering approach for chromosome conformation capture data sets identifies conserved modules of chromosomal interactions

Overview of attention for article published in Genome Biology, May 2016
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (82nd percentile)
  • Average Attention Score compared to outputs of the same age and source

Mentioned by

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18 X users
facebook
1 Facebook page

Citations

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29 Dimensions

Readers on

mendeley
72 Mendeley
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1 CiteULike
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Title
A multi-task graph-clustering approach for chromosome conformation capture data sets identifies conserved modules of chromosomal interactions
Published in
Genome Biology, May 2016
DOI 10.1186/s13059-016-0962-8
Pubmed ID
Authors

Alireza Fotuhi Siahpirani, Ferhat Ay, Sushmita Roy

Abstract

Chromosome conformation capture methods are being increasingly used to study three-dimensional genome architecture in multiple cell types and species. An important challenge is to examine changes in three-dimensional architecture across cell types and species. We present Arboretum-Hi-C, a multi-task spectral clustering method, to identify common and context-specific aspects of genome architecture. Compared to standard clustering, Arboretum-Hi-C produced more biologically consistent patterns of conservation. Most clusters are conserved and enriched for either high- or low-activity genomic signals. Most genomic regions diverge between clusters with similar chromatin state except for a few that are associated with lamina-associated domains and open chromatin.

X Demographics

X Demographics

The data shown below were collected from the profiles of 18 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 72 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Germany 1 1%
France 1 1%
Lithuania 1 1%
India 1 1%
Russia 1 1%
Unknown 67 93%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 20 28%
Researcher 19 26%
Professor 7 10%
Student > Bachelor 6 8%
Student > Master 5 7%
Other 9 13%
Unknown 6 8%
Readers by discipline Count As %
Agricultural and Biological Sciences 27 38%
Biochemistry, Genetics and Molecular Biology 20 28%
Computer Science 11 15%
Mathematics 2 3%
Engineering 2 3%
Other 3 4%
Unknown 7 10%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 10. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 18 May 2017.
All research outputs
#3,586,521
of 25,374,917 outputs
Outputs from Genome Biology
#2,471
of 4,467 outputs
Outputs of similar age
#60,691
of 353,031 outputs
Outputs of similar age from Genome Biology
#57
of 84 outputs
Altmetric has tracked 25,374,917 research outputs across all sources so far. Compared to these this one has done well and is in the 85th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 4,467 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 27.6. This one is in the 44th percentile – i.e., 44% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 353,031 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 82% of its contemporaries.
We're also able to compare this research output to 84 others from the same source and published within six weeks on either side of this one. This one is in the 30th percentile – i.e., 30% of its contemporaries scored the same or lower than it.