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Herbal medicine use and linked suspected adverse drug reactions in a prospective cohort of Ugandan inpatients

Overview of attention for article published in BMC Complementary Medicine and Therapies, May 2016
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Title
Herbal medicine use and linked suspected adverse drug reactions in a prospective cohort of Ugandan inpatients
Published in
BMC Complementary Medicine and Therapies, May 2016
DOI 10.1186/s12906-016-1125-x
Pubmed ID
Authors

Ronald Kiguba, Sam Ononge, Charles Karamagi, Sheila M. Bird

Abstract

Clinical history-taking can be employed as a standardized approach to elucidate the use of herbal medicines and their linked suspected adverse drug reactions (ADRs) among hospitalized patients. We sought to identify herbal medicines nominated by Ugandan inpatients; compare nomination rates by ward and gender; confirm the herbs' known pharmacological properties from published literature; and identify ADRs linked to pre-admission use of herbal medicines. Prospective cohort of consented adult inpatients designed to assess medication use and ADRs on one gynaecological and three medical wards of 1790-bed Mulago National Referral Hospital. Baseline and follow-up data were obtained on patients' characteristics, including pre-admission use of herbal medicines. Fourteen percent (26/191) of females in Gynaecology nominated at least one specific herbal medicine compared with 20 % (114/571) of inpatients on medical wards [20 % (69/343) of females; 20 % (45/228) of males]. Frequent nominations were Persea americana (30), Mumbwa/multiple-herb clay rods (23), Aloe barbadensis (22), Beta vulgaris (12), Vernonia amygdalina (11), Commelina africana (7), Bidens pilosa (7), Hoslundia opposita (6), Mangifera indica (4), and Dicliptera laxata (4). Four inpatients experienced 10 suspected ADRs linked to pre-admission herbal medicine use including Commelina africana (4), multiple-herb-mumbwa (1), or unspecified local-herbs (5): three ADR-cases were abortion-related and one kidney-related. The named herbal medicines and their nomination rates generally differed by specialized ward, probably guided by local folklore knowledge of their use. Clinical elicitation from inpatients can generate valuable safety data on herbal medicine use. However, larger routine studies might increase the utility of our method to assess herbal medicine use and detect herb-linked ADRs. Future studies should take testable samples of ADR-implicated herbal medicines for further analysis.

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 112 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 112 100%

Demographic breakdown

Readers by professional status Count As %
Student > Master 20 18%
Researcher 11 10%
Student > Bachelor 10 9%
Lecturer 7 6%
Student > Ph. D. Student 7 6%
Other 18 16%
Unknown 39 35%
Readers by discipline Count As %
Medicine and Dentistry 17 15%
Nursing and Health Professions 12 11%
Pharmacology, Toxicology and Pharmaceutical Science 11 10%
Agricultural and Biological Sciences 7 6%
Social Sciences 5 4%
Other 22 20%
Unknown 38 34%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 22 December 2023.
All research outputs
#17,038,804
of 25,038,941 outputs
Outputs from BMC Complementary Medicine and Therapies
#2,157
of 3,919 outputs
Outputs of similar age
#218,816
of 344,360 outputs
Outputs of similar age from BMC Complementary Medicine and Therapies
#32
of 53 outputs
Altmetric has tracked 25,038,941 research outputs across all sources so far. This one is in the 21st percentile – i.e., 21% of other outputs scored the same or lower than it.
So far Altmetric has tracked 3,919 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 9.4. This one is in the 37th percentile – i.e., 37% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 344,360 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 28th percentile – i.e., 28% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 53 others from the same source and published within six weeks on either side of this one. This one is in the 33rd percentile – i.e., 33% of its contemporaries scored the same or lower than it.