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Activity-dependent plasticity of electrical synapses: increasing evidence for its presence and functional roles in the mammalian brain

Overview of attention for article published in BMC Molecular and Cell Biology, May 2016
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Title
Activity-dependent plasticity of electrical synapses: increasing evidence for its presence and functional roles in the mammalian brain
Published in
BMC Molecular and Cell Biology, May 2016
DOI 10.1186/s12860-016-0090-z
Pubmed ID
Authors

Julie S. Haas, Corey M. Greenwald, Alberto E. Pereda

Abstract

Gap junctions mediate electrical synaptic transmission between neurons. While the actions of neurotransmitter modulators on the conductance of gap junctions have been extensively documented, increasing evidence indicates they can also be influenced by the ongoing activity of neural networks, in most cases via local interactions with nearby glutamatergic synapses. We review here early evidence for the existence of activity-dependent regulatory mechanisms as well recent examples reported in mammalian brain. The ubiquitous distribution of both neuronal connexins and the molecules involved suggest this phenomenon is widespread and represents a property of electrical transmission in general.

X Demographics

X Demographics

The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 62 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United Kingdom 1 2%
Spain 1 2%
United States 1 2%
Unknown 59 95%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 15 24%
Researcher 7 11%
Student > Master 6 10%
Student > Bachelor 6 10%
Professor 5 8%
Other 11 18%
Unknown 12 19%
Readers by discipline Count As %
Neuroscience 20 32%
Agricultural and Biological Sciences 18 29%
Biochemistry, Genetics and Molecular Biology 4 6%
Engineering 3 5%
Medicine and Dentistry 2 3%
Other 2 3%
Unknown 13 21%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 28 May 2016.
All research outputs
#17,285,668
of 25,373,627 outputs
Outputs from BMC Molecular and Cell Biology
#778
of 1,233 outputs
Outputs of similar age
#221,800
of 348,784 outputs
Outputs of similar age from BMC Molecular and Cell Biology
#12
of 22 outputs
Altmetric has tracked 25,373,627 research outputs across all sources so far. This one is in the 21st percentile – i.e., 21% of other outputs scored the same or lower than it.
So far Altmetric has tracked 1,233 research outputs from this source. They receive a mean Attention Score of 4.0. This one is in the 27th percentile – i.e., 27% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 348,784 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 28th percentile – i.e., 28% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 22 others from the same source and published within six weeks on either side of this one. This one is in the 36th percentile – i.e., 36% of its contemporaries scored the same or lower than it.