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Presentations due to acute toxicity of psychoactive substances in an urban emergency department in Switzerland: a case series

Overview of attention for article published in BMC Pharmacology and Toxicology, January 2016
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • Among the highest-scoring outputs from this source (#48 of 376)
  • High Attention Score compared to outputs of the same age (84th percentile)

Mentioned by

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19 tweeters
facebook
1 Facebook page

Citations

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12 Dimensions

Readers on

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61 Mendeley
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Title
Presentations due to acute toxicity of psychoactive substances in an urban emergency department in Switzerland: a case series
Published in
BMC Pharmacology and Toxicology, January 2016
DOI 10.1186/s40360-016-0068-7
Pubmed ID
Authors

Evangelia Liakoni, Patrick C. Dolder, Katharina M. Rentsch, Matthias E. Liechti

Abstract

Although the recreational use of psychoactive substances is common there is only limited systematic collection of data on acute drug toxicity or hospital presentations, in particular regarding novel psychoactive substances (NPS) that have emerged on the illicit market in the last years. We included all cases presenting at the emergency department (ED) of the University Hospital of Basel, Switzerland, between October 2014 and September 2015 with acute toxicity due to self-reported recreational drug use or with symptoms/signs consistent with acute toxicity. Intoxications were confirmed using immunoassays and LC-MS/MS, detecting also novel psychoactive substances. Among the 50'624 attendances at the ED, 210 were directly related to acute toxicity of recreational drugs. The mean patient age was 33 years and 73 % were male. Analytical drug confirmation was available in 136 cases. Most presentations were reportedly related to cocaine (33 %), cannabis (32 %), and heroin (14 %). The most commonly analytically detected substances were cannabis (33 %), cocaine (27 %), and opioids excluding methadone (19 %). There were only two NPS cases; a severe intoxication with paramethoxymethamphetamine (PMMA) in combination with other substances and an intoxication of minor severity with 2,5-dimethoxy-4-propylphenethylamine (2C-P). The most frequent symptoms were tachycardia (28 %), anxiety (23 %), nausea or vomiting (18 %), and agitation (17 %). Severe complications included two fatalities, two acute myocardial infarctions, seizures (13 cases), and psychosis (six cases). Most patients (76 %) were discharged home, 10 % were admitted to intensive care, and 2 % were referred to psychiatric care. Most medical problems related to illicit drugs concerned cocaine and cannabis and mainly included sympathomimetic toxicity and/or psychiatric disorders confirming data from the prior year. Importantly, despite the dramatic increase in various NPS being detected in the last years, these substances were infrequently associated with ED presentations compared with classic recreational drugs.

Twitter Demographics

The data shown below were collected from the profiles of 19 tweeters who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 61 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Switzerland 1 2%
Unknown 60 98%

Demographic breakdown

Readers by professional status Count As %
Student > Bachelor 10 16%
Student > Master 10 16%
Researcher 8 13%
Student > Ph. D. Student 6 10%
Other 6 10%
Other 13 21%
Unknown 8 13%
Readers by discipline Count As %
Medicine and Dentistry 18 30%
Pharmacology, Toxicology and Pharmaceutical Science 6 10%
Nursing and Health Professions 6 10%
Psychology 6 10%
Biochemistry, Genetics and Molecular Biology 3 5%
Other 10 16%
Unknown 12 20%

Attention Score in Context

This research output has an Altmetric Attention Score of 11. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 03 June 2017.
All research outputs
#2,362,505
of 19,215,644 outputs
Outputs from BMC Pharmacology and Toxicology
#48
of 376 outputs
Outputs of similar age
#43,151
of 276,507 outputs
Outputs of similar age from BMC Pharmacology and Toxicology
#2
of 3 outputs
Altmetric has tracked 19,215,644 research outputs across all sources so far. Compared to these this one has done well and is in the 87th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 376 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 5.6. This one has done well, scoring higher than 87% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 276,507 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 84% of its contemporaries.
We're also able to compare this research output to 3 others from the same source and published within six weeks on either side of this one.