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Longitudinal MRI contrast enhanced monitoring of early tumour development with manganese chloride (MnCl2) and superparamagnetic iron oxide nanoparticles (SPIOs) in a CT1258 based in vivo model of…

Overview of attention for article published in BMC Cancer, July 2012
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Title
Longitudinal MRI contrast enhanced monitoring of early tumour development with manganese chloride (MnCl2) and superparamagnetic iron oxide nanoparticles (SPIOs) in a CT1258 based in vivo model of prostate cancer
Published in
BMC Cancer, July 2012
DOI 10.1186/1471-2407-12-284
Pubmed ID
Authors

Katharina A Sterenczak, Martin Meier, Silke Glage, Matthias Meyer, Saskia Willenbrock, Patrick Wefstaedt, Martina Dorsch, Jörn Bullerdiek, Hugo Murua Escobar, Hans Hedrich, Ingo Nolte

Abstract

Cell lines represent a key tool in cancer research allowing the generation of neoplasias which resemble initial tumours in in-vivo animal models. The characterisation of early tumour development is of major interest in order to evaluate the efficacy of therapeutic agents. Magnetic resonance imaging (MRI) based in-vivo characterisation allows visualisation and characterisation of tumour development in early stages prior to manual palpation. Contrast agents for MRI such as superparamagnetic iron oxide nanoparticles (SPIOs) and manganese chloride (MnCl2) represent powerful tools for the in-vivo characterisation of early stage tumours. In this experimental study, we labelled prostate cancer cells with MnCl2 or SPIOs in vitro and used 1 T MRI for tracing labelled cells in-vitro and 7 T MRI for tracking in an in-vivo animal model.

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The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 34 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Canada 1 3%
Unknown 33 97%

Demographic breakdown

Readers by professional status Count As %
Student > Bachelor 8 24%
Student > Doctoral Student 5 15%
Student > Ph. D. Student 4 12%
Researcher 4 12%
Student > Master 3 9%
Other 5 15%
Unknown 5 15%
Readers by discipline Count As %
Medicine and Dentistry 7 21%
Engineering 4 12%
Physics and Astronomy 4 12%
Biochemistry, Genetics and Molecular Biology 3 9%
Computer Science 2 6%
Other 5 15%
Unknown 9 26%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 11 July 2012.
All research outputs
#18,310,549
of 22,671,366 outputs
Outputs from BMC Cancer
#5,415
of 8,243 outputs
Outputs of similar age
#126,579
of 164,330 outputs
Outputs of similar age from BMC Cancer
#64
of 79 outputs
Altmetric has tracked 22,671,366 research outputs across all sources so far. This one is in the 11th percentile – i.e., 11% of other outputs scored the same or lower than it.
So far Altmetric has tracked 8,243 research outputs from this source. They receive a mean Attention Score of 4.3. This one is in the 21st percentile – i.e., 21% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 164,330 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 9th percentile – i.e., 9% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 79 others from the same source and published within six weeks on either side of this one. This one is in the 2nd percentile – i.e., 2% of its contemporaries scored the same or lower than it.