Title |
From “traction bronchiectasis” to honeycombing in idiopathic pulmonary fibrosis: A spectrum of bronchiolar remodeling also in radiology?
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Published in |
BMC Pulmonary Medicine, May 2016
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DOI | 10.1186/s12890-016-0245-x |
Pubmed ID | |
Authors |
Sara Piciucchi, Sara Tomassetti, Claudia Ravaglia, Christian Gurioli, Carlo Gurioli, Alessandra Dubini, Angelo Carloni, Marco Chilosi, Thomas V Colby, Venerino Poletti |
Abstract |
The diagnostic and prognostic impact of traction bronchiectasis on high resolution CT scan (HRCT) in patients suspected to have idiopathic pulmonary fibrosis (IPF) is increasing significantly. Recent data demonstrated that cysts in honeycombing areas are covered by epithelium expressing bronchiolar markers. In IPF bronchiolization is the final consequence of a variety of pathogenic events starting from alveolar stem cell exhaustion, and ending in a abnormal/dysplastic proliferation of bronchiolar epithelium. CT scan features of traction bronchiectasis and honeycombing should be interpreted under the light of these new pathogenetic and morphologic considerations. We suggest that in IPF subjects traction bronchiectasis and honeycombing -now defined as distinct entities on HRCT scan- are actually diverse aspects of a continuous spectrum of lung remodeling. |
X Demographics
Geographical breakdown
Country | Count | As % |
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United States | 3 | 30% |
France | 1 | 10% |
Turkey | 1 | 10% |
Israel | 1 | 10% |
Unknown | 4 | 40% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 5 | 50% |
Practitioners (doctors, other healthcare professionals) | 3 | 30% |
Scientists | 2 | 20% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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Unknown | 58 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
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Researcher | 9 | 16% |
Student > Bachelor | 7 | 12% |
Other | 6 | 10% |
Student > Doctoral Student | 4 | 7% |
Student > Ph. D. Student | 4 | 7% |
Other | 14 | 24% |
Unknown | 14 | 24% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 30 | 52% |
Biochemistry, Genetics and Molecular Biology | 3 | 5% |
Agricultural and Biological Sciences | 2 | 3% |
Immunology and Microbiology | 2 | 3% |
Computer Science | 1 | 2% |
Other | 3 | 5% |
Unknown | 17 | 29% |