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Mendeley readers
Attention Score in Context
| Title |
Risk of hip fracture among older people using antihypertensive drugs: a nationwide cohort study
|
|---|---|
| Published in |
BMC Geriatrics, December 2015
|
| DOI | 10.1186/s12877-015-0154-5 |
| Pubmed ID | |
| Authors |
Sabine Ruths, Marit S. Bakken, Anette H. Ranhoff, Steinar Hunskaar, Lars B. Engesæter, Anders Engeland |
| Abstract |
Many people with a high risk of hip fracture have coexisting cardiovascular diseases. We aimed to examine associations between exposure to antihypertensive drugs and the risk of hip fracture among older people. We conducted a cohort study of the 906,422 people born before 1945 and living in Norway in 2005. We obtained information on all prescriptions of antihypertensive drugs dispensed (the Norwegian Prescription Database) in 2004-2010 and the dates of primary hip fractures (the Norwegian Hip Fracture Registry) in 2005-2010. We compared the incidence rates of hip fracture during the time people were exposed and unexposed to antihypertensive drugs by calculating the standardized incidence ratio (SIR). Altogether, 39,938 people experienced a primary hip fracture (4.4 %). The risk of hip fracture was decreased among people exposed to thiazides (SIR 0.7, 95 % confidence interval (CI) 0.6-0.7), beta-blockers (SIR 0.7, 95 % CI 0.7-0.8), calcium channel blockers (SIR 0.8, 95 % CI 0.8-0.8), angiotensin II receptor blockers (SIR 0.8, 95 % CI 0.7-0.8), ACE inhibitor/thiazide combination products (SIR 0.7, 95 % CI 0.6-0.7) and angiotensin II receptor blocker/thiazide combination products (SIR 0.6, 95 % CI 0.6-0.6). Use of loop diuretics and ACE inhibitors (plain products) was associated with increased fracture risk in people born after 1924, and with decreased risk in those born before 1925. The protective associations were stronger among exposed men than among exposed women for all drugs except loop diuretics. The SIRs decreased with increasing age among exposed people, except for thiazides and angiotensin II receptor blockers. We found a reduced risk of hip fracture associated with overall use of most antihypertensive drugs, but an increased risk with loop diuretics and ACE inhibitors among people younger than 80 years and in new users of loop diuretics. This may have great impact at the population level, because the use of antihypertensive drugs is widespread in people at risk of hip fracture. Clinical studies are needed to further explore these associations. |
X Demographics
The data shown below were collected from the profiles of 4 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United Kingdom | 1 | 25% |
| Norway | 1 | 25% |
| Unknown | 2 | 50% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 4 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 56 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 56 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Researcher | 10 | 18% |
| Student > Master | 8 | 14% |
| Student > Bachelor | 7 | 13% |
| Student > Postgraduate | 5 | 9% |
| Student > Ph. D. Student | 4 | 7% |
| Other | 7 | 13% |
| Unknown | 15 | 27% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 22 | 39% |
| Biochemistry, Genetics and Molecular Biology | 4 | 7% |
| Nursing and Health Professions | 4 | 7% |
| Agricultural and Biological Sciences | 2 | 4% |
| Materials Science | 2 | 4% |
| Other | 4 | 7% |
| Unknown | 18 | 32% |
Attention Score in Context
This research output has an Altmetric Attention Score of 3. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 05 October 2016.
All research outputs
#13,423,124
of 23,170,347 outputs
Outputs from BMC Geriatrics
#1,993
of 3,280 outputs
Outputs of similar age
#183,869
of 389,227 outputs
Outputs of similar age from BMC Geriatrics
#38
of 58 outputs
Altmetric has tracked 23,170,347 research outputs across all sources so far. This one is in the 41st percentile – i.e., 41% of other outputs scored the same or lower than it.
So far Altmetric has tracked 3,280 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 9.4. This one is in the 38th percentile – i.e., 38% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 389,227 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 52% of its contemporaries.
We're also able to compare this research output to 58 others from the same source and published within six weeks on either side of this one. This one is in the 34th percentile – i.e., 34% of its contemporaries scored the same or lower than it.