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Sialylated glycans as receptor and inhibitor of enterovirus 71 infection to DLD-1 intestinal cells

Overview of attention for article published in Virology Journal, September 2009
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1 X user
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5 Facebook pages

Citations

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137 Dimensions

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80 Mendeley
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Title
Sialylated glycans as receptor and inhibitor of enterovirus 71 infection to DLD-1 intestinal cells
Published in
Virology Journal, September 2009
DOI 10.1186/1743-422x-6-141
Pubmed ID
Authors

Betsy Yang, Hau Chuang, Kuender D Yang

Abstract

Many viruses recognize specific sugar residues, particularly sulfated or sialylated glycans, as the infection receptors. A change of sialic acid (2-6)-linked galactose (SA-alpha2,6Gal) to SA-alpha2,3Gal determines the receptor for avian flu infection. The receptor for enterovirus 71 (EV71) infection that frequently causes fatal encephalitis in Asian children remains unclear. Currently, there is no effective vaccine or anti-virus agent for EV71 infection. Using DLD-1 intestinal cells, this study investigated whether SA-linked glycan on DLD-1 intestinal cells was a receptor for EV71, and whether natural SA-linked sugars from human milk could block EV71 infection.

X Demographics

X Demographics

The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 80 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United Kingdom 1 1%
Poland 1 1%
Unknown 78 98%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 18 23%
Student > Bachelor 17 21%
Researcher 11 14%
Student > Master 10 13%
Student > Postgraduate 5 6%
Other 7 9%
Unknown 12 15%
Readers by discipline Count As %
Agricultural and Biological Sciences 17 21%
Biochemistry, Genetics and Molecular Biology 13 16%
Medicine and Dentistry 10 13%
Chemistry 7 9%
Immunology and Microbiology 6 8%
Other 12 15%
Unknown 15 19%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 3. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 21 August 2018.
All research outputs
#14,914,476
of 25,374,647 outputs
Outputs from Virology Journal
#1,463
of 3,391 outputs
Outputs of similar age
#86,366
of 105,685 outputs
Outputs of similar age from Virology Journal
#26
of 29 outputs
Altmetric has tracked 25,374,647 research outputs across all sources so far. This one is in the 40th percentile – i.e., 40% of other outputs scored the same or lower than it.
So far Altmetric has tracked 3,391 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 24.6. This one has gotten more attention than average, scoring higher than 55% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 105,685 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 18th percentile – i.e., 18% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 29 others from the same source and published within six weeks on either side of this one. This one is in the 10th percentile – i.e., 10% of its contemporaries scored the same or lower than it.