Title |
A microRNA activity map of human mesenchymal tumors: connections to oncogenic pathways; an integrative transcriptomic study
|
---|---|
Published in |
BMC Genomics, July 2012
|
DOI | 10.1186/1471-2164-13-332 |
Pubmed ID | |
Authors |
Elena Fountzilas, Andrew D Kelly, Antonio R Perez-Atayde, Jeffrey Goldsmith, Panagiotis A Konstantinopoulos, Nancy Francoeur, Mick Correll, Renee Rubio, Lan Hu, Mark C Gebhardt, John Quackenbush, Dimitrios Spentzos |
Abstract |
MicroRNAs (miRNAs) are nucleic acid regulators of many human mRNAs, and are associated with many tumorigenic processes. miRNA expression levels have been used in profiling studies, but some evidence suggests that expression levels do not fully capture miRNA regulatory activity. In this study we integrate multiple gene expression datasets to determine miRNA activity patterns associated with cancer phenotypes and oncogenic pathways in mesenchymal tumors - a very heterogeneous class of malignancies. |
X Demographics
Geographical breakdown
Country | Count | As % |
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France | 1 | 100% |
Demographic breakdown
Type | Count | As % |
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Scientists | 1 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
France | 1 | 4% |
Unknown | 26 | 96% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Researcher | 7 | 26% |
Student > Ph. D. Student | 4 | 15% |
Professor > Associate Professor | 3 | 11% |
Student > Bachelor | 3 | 11% |
Professor | 2 | 7% |
Other | 3 | 11% |
Unknown | 5 | 19% |
Readers by discipline | Count | As % |
---|---|---|
Agricultural and Biological Sciences | 7 | 26% |
Medicine and Dentistry | 6 | 22% |
Biochemistry, Genetics and Molecular Biology | 4 | 15% |
Engineering | 2 | 7% |
Computer Science | 1 | 4% |
Other | 2 | 7% |
Unknown | 5 | 19% |