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Expression of iron-related genes in human brain and brain tumors

Overview of attention for article published in BMC Neuroscience, April 2009
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Title
Expression of iron-related genes in human brain and brain tumors
Published in
BMC Neuroscience, April 2009
DOI 10.1186/1471-2202-10-36
Pubmed ID
Authors

Milla M Hänninen, Joonas Haapasalo, Hannu Haapasalo, Robert E Fleming, Robert S Britton, Bruce R Bacon, Seppo Parkkila

Abstract

Defective iron homeostasis may be involved in the development of some diseases within the central nervous system. Although the expression of genes involved in normal iron balance has been intensively studied in other tissues, little is known about their expression in the brain. We investigated the mRNA levels of hepcidin (HAMP), HFE, neogenin (NEO1), transferrin receptor 1 (TFRC), transferrin receptor 2 (TFR2), and hemojuvelin (HFE2) in normal human brain, brain tumors, and astrocytoma cell lines. The specimens included 5 normal brain tissue samples, 4 meningiomas, one medulloblastoma, 3 oligodendrocytic gliomas, 2 oligoastrocytic gliomas, 8 astrocytic gliomas, and 3 astrocytoma cell lines.

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X Demographics

The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 60 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Slovakia 1 2%
Canada 1 2%
Unknown 58 97%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 15 25%
Researcher 9 15%
Student > Master 7 12%
Student > Doctoral Student 5 8%
Lecturer 4 7%
Other 11 18%
Unknown 9 15%
Readers by discipline Count As %
Medicine and Dentistry 17 28%
Biochemistry, Genetics and Molecular Biology 11 18%
Agricultural and Biological Sciences 10 17%
Neuroscience 6 10%
Unspecified 1 2%
Other 5 8%
Unknown 10 17%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 23 July 2012.
All research outputs
#15,247,248
of 22,671,366 outputs
Outputs from BMC Neuroscience
#704
of 1,240 outputs
Outputs of similar age
#78,687
of 93,240 outputs
Outputs of similar age from BMC Neuroscience
#9
of 12 outputs
Altmetric has tracked 22,671,366 research outputs across all sources so far. This one is in the 22nd percentile – i.e., 22% of other outputs scored the same or lower than it.
So far Altmetric has tracked 1,240 research outputs from this source. They receive a mean Attention Score of 4.3. This one is in the 34th percentile – i.e., 34% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 93,240 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 8th percentile – i.e., 8% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 12 others from the same source and published within six weeks on either side of this one. This one is in the 16th percentile – i.e., 16% of its contemporaries scored the same or lower than it.