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X Demographics
Mendeley readers
Attention Score in Context
| Title |
The ubiquitin–proteasome system and signal transduction pathways regulating Epithelial Mesenchymal transition of cancer
|
|---|---|
| Published in |
Journal of Biomedical Science, July 2012
|
| DOI | 10.1186/1423-0127-19-67 |
| Pubmed ID | |
| Authors |
Ioannis A Voutsadakis |
| Abstract |
Epithelial to Mesenchymal transition (EMT) in cancer, a process permitting cancer cells to become mobile and metastatic, has a signaling hardwire forged from development. Multiple signaling pathways that regulate carcinogenesis enabling characteristics in neoplastic cells such as proliferation, resistance to apoptosis and angiogenesis are also the main players in EMT. These pathways, as almost all cellular processes, are in their turn regulated by ubiquitination and the Ubiquitin-Proteasome System (UPS). Ubiquitination is the covalent link of target proteins with the small protein ubiquitin and serves as a signal to target protein degradation by the proteasome or to other outcomes such as endocytosis, degradation by the lysosome or specification of cellular localization. This paper reviews signal transduction pathways regulating EMT and being regulated by ubiquitination. |
X Demographics
The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 1 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 1 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 79 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Portugal | 1 | 1% |
| Korea, Republic of | 1 | 1% |
| United Kingdom | 1 | 1% |
| Iran, Islamic Republic of | 1 | 1% |
| United States | 1 | 1% |
| Unknown | 74 | 94% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Researcher | 18 | 23% |
| Student > Ph. D. Student | 17 | 22% |
| Student > Master | 15 | 19% |
| Student > Bachelor | 7 | 9% |
| Other | 7 | 9% |
| Other | 9 | 11% |
| Unknown | 6 | 8% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 31 | 39% |
| Biochemistry, Genetics and Molecular Biology | 24 | 30% |
| Medicine and Dentistry | 6 | 8% |
| Chemistry | 3 | 4% |
| Pharmacology, Toxicology and Pharmaceutical Science | 2 | 3% |
| Other | 3 | 4% |
| Unknown | 10 | 13% |
Attention Score in Context
This research output has an Altmetric Attention Score of 7. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 16 March 2022.
All research outputs
#4,835,823
of 25,373,627 outputs
Outputs from Journal of Biomedical Science
#196
of 1,101 outputs
Outputs of similar age
#32,445
of 178,824 outputs
Outputs of similar age from Journal of Biomedical Science
#3
of 12 outputs
Altmetric has tracked 25,373,627 research outputs across all sources so far. Compared to these this one has done well and is in the 79th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 1,101 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 11.0. This one has done well, scoring higher than 81% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 178,824 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 80% of its contemporaries.
We're also able to compare this research output to 12 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 75% of its contemporaries.