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Serotype epidemiology and multidrug resistance patterns of Salmonellaenterica infecting humans in Italy

Overview of attention for article published in Gut Pathogens, June 2016
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Title
Serotype epidemiology and multidrug resistance patterns of Salmonellaenterica infecting humans in Italy
Published in
Gut Pathogens, June 2016
DOI 10.1186/s13099-016-0110-8
Pubmed ID
Authors

Ilaria Frasson, Sabrina Bettanello, Ettore De Canale, Sara N. Richter, Giorgio Palù

Abstract

Salmonella enterica is the zoonotic agent most frequently responsible for foodborne infections in humans worldwide. In this work the presence of S. enterica was investigated in 734 unique enteropathogenic isolates collected from human patients between 2011 and 2012. All Salmonella spp. isolates were subjected to serotyping and antimicrobial susceptibility testing. Isolates displaying phenotypes and antimicrobial susceptibility profiles different from the reference strains were genotipically characterized. Several plasmid-embedded resistance determinants were identified and characterized. Non-typhoidal serotypes were most frequently diagnosed; monophasic Salmonella typhimurium 1,4 [5],12:i- and S. typhimurium represented the most prevalent serovars. Five isolates displayed phenotypes with extremely reduced susceptibility to antimicrobials: we detected multidrug resistance elements belonging to Ambler class A and class C in two non-typhoidal S. enterica serovars, i.e. Rissen and monophasic S. typhimurium 1,4 [5],12:i-, and in one typhoidal serovar, i.e., Paratyphi B. These resistance determinants have been so far almost exclusively associated with non-Salmonella members of the Enterobacteriaceae family. Alarmingly, two colistin resistant Salmonella enteritidis were also found. This work draws the attention to the still low, but rising, percentage of multidrug resistant Salmonella isolates infecting humans in Italy. Our results suggest that prompt monitoring of Salmonella serovar dissemination and resistance to antimicrobials is highly required.

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 26 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 26 100%

Demographic breakdown

Readers by professional status Count As %
Researcher 8 31%
Student > Master 7 27%
Student > Doctoral Student 2 8%
Student > Ph. D. Student 1 4%
Lecturer 1 4%
Other 2 8%
Unknown 5 19%
Readers by discipline Count As %
Agricultural and Biological Sciences 4 15%
Veterinary Science and Veterinary Medicine 3 12%
Biochemistry, Genetics and Molecular Biology 3 12%
Immunology and Microbiology 3 12%
Medicine and Dentistry 3 12%
Other 2 8%
Unknown 8 31%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 09 June 2016.
All research outputs
#18,462,696
of 22,876,619 outputs
Outputs from Gut Pathogens
#383
of 523 outputs
Outputs of similar age
#254,746
of 339,120 outputs
Outputs of similar age from Gut Pathogens
#18
of 22 outputs
Altmetric has tracked 22,876,619 research outputs across all sources so far. This one is in the 11th percentile – i.e., 11% of other outputs scored the same or lower than it.
So far Altmetric has tracked 523 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 7.8. This one is in the 8th percentile – i.e., 8% of its peers scored the same or lower than it.
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We're also able to compare this research output to 22 others from the same source and published within six weeks on either side of this one. This one is in the 4th percentile – i.e., 4% of its contemporaries scored the same or lower than it.