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HIV infection, viral hepatitis and liver fibrosis among prison inmates in West Africa

Overview of attention for article published in BMC Infectious Diseases, June 2016
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Title
HIV infection, viral hepatitis and liver fibrosis among prison inmates in West Africa
Published in
BMC Infectious Diseases, June 2016
DOI 10.1186/s12879-016-1601-4
Pubmed ID
Authors

Antoine Jaquet, Gilles Wandeler, Judicaël Tine, Claver A. Dagnra, Alain Attia, Akouda Patassi, Abdoulaye Ndiaye, Victor de Ledinghen, Didier K. Ekouevi, Moussa Seydi, François Dabis

Abstract

Prisoners represent a vulnerable population for blood-borne and sexually transmitted infections which can potentially lead to liver fibrosis and ultimately cirrhosis. However, little is known about the prevalence of liver fibrosis and associated risk factors among inmates in sub-Saharan Africa. Screening of liver fibrosis was undertaken in a randomly selected sample of male inmates incarcerated in Lome, Togo and in Dakar, Senegal using transient elastography. A liver stiffness measurement ≥9.5 KPa was retained to define the presence of a severe liver fibrosis. All included inmates were also screened for HIV, Hepatitis B Virus (HBV) and Hepatitis C Virus (HCV) infection. Substances abuse including alcohol, tobacco and cannabis use were assessed during face-to-face interviews. Odds Ratio (OR) estimates were computed with their 95 % Confidence Interval (CI) to identify factors associated with severe liver fibrosis. Overall, 680 inmates were included with a median age of 30 years [interquartile range: 24-35]. The prevalence of severe fibrosis was 3.1 % (4.9 % in Lome and 1.2 % in Dakar). Infections with HIV, HBV and HCV were identified in 2.6 %, 12.5 % and 0.5 % of inmates, respectively. Factors associated with a severe liver fibrosis were HIV infection (OR = 7.6; CI 1.8-32.1), HBV infection (OR = 4.8; CI 1.8-12.8), HCV infection (OR = 52.6; CI 4.1-673.8), use of traditional medicines (OR = 3.7; CI 1.4-10.1) and being incarcerated in Lome (OR = 3.3; CI 1.1-9.8) compared to Dakar. HIV infection and viral hepatitis infections were identified as important and independent determinants of severe liver fibrosis. While access to active antiviral therapies against HIV and viral hepatitis expands in Africa, adapted strategies for the monitoring of liver disease need to be explored, especially in vulnerable populations such as inmates.

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The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 119 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Spain 1 <1%
Unknown 118 99%

Demographic breakdown

Readers by professional status Count As %
Student > Master 20 17%
Other 8 7%
Researcher 8 7%
Student > Postgraduate 8 7%
Student > Bachelor 8 7%
Other 22 18%
Unknown 45 38%
Readers by discipline Count As %
Medicine and Dentistry 33 28%
Nursing and Health Professions 11 9%
Immunology and Microbiology 5 4%
Social Sciences 5 4%
Agricultural and Biological Sciences 3 3%
Other 14 12%
Unknown 48 40%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 12 June 2016.
All research outputs
#17,807,987
of 22,877,793 outputs
Outputs from BMC Infectious Diseases
#5,125
of 7,691 outputs
Outputs of similar age
#241,707
of 340,764 outputs
Outputs of similar age from BMC Infectious Diseases
#96
of 149 outputs
Altmetric has tracked 22,877,793 research outputs across all sources so far. This one is in the 19th percentile – i.e., 19% of other outputs scored the same or lower than it.
So far Altmetric has tracked 7,691 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 9.6. This one is in the 26th percentile – i.e., 26% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 340,764 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 24th percentile – i.e., 24% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 149 others from the same source and published within six weeks on either side of this one. This one is in the 30th percentile – i.e., 30% of its contemporaries scored the same or lower than it.