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Nonstructural protein 11 (nsp11) of porcine reproductive and respiratory syndrome virus (PRRSV) promotes PRRSV infection in MARC-145 cells

Overview of attention for article published in BMC Veterinary Research, June 2016
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1 tweeter

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Title
Nonstructural protein 11 (nsp11) of porcine reproductive and respiratory syndrome virus (PRRSV) promotes PRRSV infection in MARC-145 cells
Published in
BMC Veterinary Research, June 2016
DOI 10.1186/s12917-016-0717-5
Pubmed ID
Authors

Xibao Shi, Xiaozhuan Zhang, Yongzhe Chang, Bo Jiang, Ruiguang Deng, Aiping Wang, Gaiping Zhang

Abstract

Porcine reproductive and respiratory syndrome virus (PRRSV) induces one of most important devastating disease of swine worldwide, and the current methods poorly control it. Previous studies have indicated that the nonstructural protein 11 (nsp11) of PRRSV may be an important protein for the immune escape of PRRSV. Here, we firstly explored the effect of over-expression of nsp11 on PRRSV infection and found that over-expression of nsp11 enhanced the PRRSV titers while the small interfering RNA (siRNAs) specifically targeting nsp11 could reduce the PRRSV titers in MARC-145 cells. In conclusion, PRRSV nsp11 promotes PRRSV infection in MARC-145 cells and siRNAs targeting nsp11 may be a potential therapeutic strategy to control PRRSV in future.

Twitter Demographics

The data shown below were collected from the profile of 1 tweeter who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 11 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 11 100%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 4 36%
Researcher 2 18%
Student > Master 2 18%
Professor 1 9%
Student > Bachelor 1 9%
Other 0 0%
Unknown 1 9%
Readers by discipline Count As %
Agricultural and Biological Sciences 3 27%
Biochemistry, Genetics and Molecular Biology 3 27%
Veterinary Science and Veterinary Medicine 1 9%
Computer Science 1 9%
Immunology and Microbiology 1 9%
Other 0 0%
Unknown 2 18%

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 13 June 2016.
All research outputs
#5,984,354
of 7,890,722 outputs
Outputs from BMC Veterinary Research
#746
of 1,191 outputs
Outputs of similar age
#187,263
of 267,818 outputs
Outputs of similar age from BMC Veterinary Research
#43
of 67 outputs
Altmetric has tracked 7,890,722 research outputs across all sources so far. This one is in the 13th percentile – i.e., 13% of other outputs scored the same or lower than it.
So far Altmetric has tracked 1,191 research outputs from this source. They receive a mean Attention Score of 2.6. This one is in the 19th percentile – i.e., 19% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 267,818 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 16th percentile – i.e., 16% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 67 others from the same source and published within six weeks on either side of this one. This one is in the 14th percentile – i.e., 14% of its contemporaries scored the same or lower than it.